Cell physiology - part 2 Flashcards

1
Q

excitation (ions)

A

increase Na+ and Ca+

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2
Q

inhibition (ions)

A

increase K+ and Cl-

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3
Q

excited area

A

depolarised

more positive inside

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4
Q

resting area

A

polarised

more negative inside

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5
Q

saltatory conduction

A

impulses jump Schwann cells from node to node of Ranvier, faster

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6
Q

what are nerves made up of

A

neuroglia/ glia
epineurium
perineurium
endoneurium

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7
Q

neuroglia/ glia

A

non-neural cells maintain homeostasis by forming myelin (insulate, supply O2, hold neuron in place)

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8
Q

epineurium

A

dense sheath of connective tissue covers each nerve

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9
Q

perineurium

A

layer surrounds bundles of axons

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10
Q

endoneurium

A

cover surrounding each fibre

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11
Q

EPSP

A

excitatory post synaptic potential
depolarisation
glutamate, acetylcholine
Na+ in, K+ out

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12
Q

IPSP

A

inhibitory post synaptic potential
hyperpolarisation
GABA, glycine
Cl- or K+ in

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13
Q

summation

A

combination of EPSP and IPSP

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14
Q

EPSP-IPSP cancellation

A

cancel each other out

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15
Q

EPSP spatial summation

A

EPSP from different neurons trigger threshold point

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16
Q

EPSP temporal summation

A

two EPSP from same neuron trigger threshold point

17
Q

composite post synaptic potential

A

all EPSPs and IPSP occur at the same time

18
Q

3 types of muscle

A

cardiac muscle
smooth muscle
skeletal muscle

19
Q

cardiac muscle

A

branched, unaligned fibres
gaps between allow for contraction
gap junction - exchange of small molecules
desmosomes (anchoring junction) - mechanical strength, keratin

20
Q

smooth muscle

A

spindle shaped, non-striated

21
Q

types of skeletal muscle

A

red muscle
white muscle
mixed muscle

22
Q

skeletal muscle

A

myofibrils (contractile fibres) are striated, aligned

23
Q

red muscle

A

skeletal muscle
highly vascular, many mitochondria and myoglobin
aerobic
slow contractility

24
Q

white muscle

A

skeletal muscle
not very vascular, not many mitochonria and myoglobin
anaerobic
faster contractility

25
Q

titin filaments

A

elastic protein chain keep filaments aligned

26
Q

syncytium

A
multicellular cell from fusion of many unicellular cells 
structtural syncytium - skeletal muscle
function syncytium - cardiac and smooth muscle
27
Q

phases of muscle contraction

A
contraction is depolarisation
excitation stimulates Na+ open 
Ca2+ open, Ca2+ in 
Ca2+ induce receptors on sarcoplasmic reticulum (SR) to secrete more Ca2+ (positive feedback)
Ca2+ stimulate contractile apparatus
28
Q

phases of muscle relaxation

A

relaxation is repolarisation
Ca2+ reuptake into sarcoplasmic reticulum (SR)
Na+/ Ca2+ exchanger (NCX): 2Na+ in, 1Ca2+ out
Na+/ K+ ATPase: 3Na+ out, 2K+ in
activation of K+ channels

29
Q

control of muscles

A

Ca2+ homeostasis from internal stores in sarcoplasmic reticulum (SR)

30
Q

latent period

A

time between stimulus and contraction

31
Q

excitation of muscles

A

twitch - single muscle contraction
wave summation - muscle does not completely relax between successive stimulations
incomplete tetanus - partial relaxation between increased frequency of stimulations
complete tetanus - no relaxation, complete contraction, maximal contraction