Cartilage Flashcards

1
Q

actuando como molde para casi todos los huesos adultos proceso llamado

A

Osificacion endocondral

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2
Q

Envoltura de TC fibroso ricamente vascularizado , que rodea por completo al cartílago a excepción del plano de fricción del cartílago articular y parenquima de tejido cartilaginoso, denominado

A

Pericondrio

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3
Q

Capas del Pericondrio

A

Una externa o fibrosa y celular o interna

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4
Q

Características de capa externa o fibrosa del Pericondrio

A

Abundantes fibras de colageno, venas y arteriolas

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5
Q

Características de capa interna o celular de Pericondrio

A

Fibroblastos y celulas precursoras de cartílago

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6
Q

Celulas del cartílago

A

Condrocitos

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7
Q

Se encuentran mezclados en matriz de sustancia fundamental y fibras conjuntivas pero carece de vasos sanguíneos

A

Condrocitos

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8
Q

Cartílago es

A

Avascular

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9
Q

Los Condrocitos maduros se encuentran en una matriz aislados llamada

A

Laguna condroide

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10
Q

Celulas grandes y redondeadas con núcleo central y citoplasma abundante , cuyo aspecto varía de basofilos a acidofilos según las células estén en fase de síntesis o reposo

A

Condrocitos

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11
Q

Los Condrocitos proceden de la proliferación y diferenciación de los

A

Condroblastos

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12
Q

Se sitúan en la capa celular mas interna próxima a la matriz del Pericondrio

A

Condroblastos

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13
Q

Los Condroblastos quedan envueltos por matriz y siguen sufriendo mitosis aparecen localizados en una sola laguna o con tabiques de separación

A

Grupos isogenicos

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14
Q

Grupos isogenicos más abundantes en

A

Cartílago inmaduro

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15
Q

Matriz o cápsula basofila próxima a los Condroblastos o Condrocitos

A

Cápsula o matriz territorial

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16
Q

Matriz levemente acidofilas

A

Matriz interterritorial

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17
Q

Dentro de la matriz territorial la parte en contacto con el condrocito se muestra más basofila y es

A

Metacromatica con azul de toluidina

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18
Q

La sustancia fundamental de la matriz es amorfa y rica en proteoglycanos especialmente

A

Condroitin 4 sulfato y condroitin 6 sulfato debido a esto provoca metachromasia

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19
Q

Tipo de fibras de colageno que se pueden encontrar, que se disponen en forma de cestas en la matriz territorial alrededor de los condrocitos y formando haces lineales en la matriz interterritorial

A

II,IX,XI y fibras elásticas

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20
Q

Tres tipos de cartílago

A

Hialino, elástico,fibrocartilago

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21
Q

Matriz extracelular es transparente y lisa como el cristal

A

Cartílago hialino

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22
Q

Contiene fibras de colageno y sustancia fundamental abundante , Condrocitos separados por la matriz

A

Cartílago hialino

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23
Q

Dos variedades de cartílago hialino

A

Cartílago articular y el que forma placas metafisiarias

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24
Q

Forma los planos de fricción de articulaciones moviles(diartrosis) , ausencia de Pericondrio en los puntos de rozamiento

A

Cartílago articular

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25
Se encuentra en constante formación en un extremo y en destrucción y sustitución por tejido óseo en el opuesto
Cartílago de crecimiento
26
Fibras de colageno elemento más abundante , Condrocitos dispersos entre las fibras de colageno y en dirección orientadas a los fascículos fibrosos
Cartílago fibroso o fibrocartilago
27
Predominio de fibras elásticas dispuestas en placas y sustancia fundamental poco abundante ,Condrocitos amontonados
Cartílago elástico
28
Donde se encuentra el cartílago elástico
Laringe( epiglotis,cartílagos corniculados y cuneiformes,aritenoides,y sésamo ideo) Tabique nasal Pabellón auricular
29
Se puede reconocer por una serie de "cabellos" o "pelusas" rosas o moradas alrededor de los Condrocitos
Cartílago elástico
30
Forma el esqueleto fetal y de los individuos neonatos actuando como molde para casi todos los huesos adultos
Cartílago
31
The most common form of collagen , the principal collagen type
Collagen type II
32
Harbors the cartilage vascular supply and nerves and lymphatic vessels
Perichondrium
33
Cartilage more common
Hyaline
34
Location of Hyaline cartilage
Respiratory passages( nose, larynx,trachea,bronchi) Ventral ends Ribs Epiphyseal plates of long Bones Articular surfaces
35
A chronic condition commonly in aging , the gradual loss or changed physical properties of Hyaline cartilage that lines the articular ends of Bones in joints
Osteoarthritis
36
The dry weight of Hyaline cartilage
40% collagen embedded in a firm hydrated gel of proteoglycans and structural glycoproteins
37
Most of the collagen in Hyaline cartilage is
Type II
38
Most abundant proteoglycan of Hyaline cartilage with approximately 150 GAGs side chain of chondroitin sulfate and keratan sulfate
Aggrecan
39
% of the weight of Hyaline cartilage is water
75%
40
Water bound to GAGs in the proteoglycans constituted
60% to 80% of the weight of fresh Hyaline cartilage
41
Important components of cartilage matrix is the structural multiadhesive glycoprotein
Chondroitin
42
Chondroitin binds to....., mediating the adherence of chondrocytes to the ECM
GAGs,collagen type II, and integrins
43
Surrounding each chondrocytes the ECM is relatively richer in GAGs, often causing these áreas of
Territorial matrix
44
Hyaline cartilage cells metabolize glucose by anaerobic glycolysis to produce
Lactic acid
45
Transport of water and solutes in the matrix is promoted by the pumping action of intermittent cartilage
Compression and decompression
46
The inability of cartilage to regenerate or to be repair may be atributed to
Chondrocytes immobility, low metabolic and mitotic rates and avascularity
47
A major regulator of hyaline cartilage growth is pituitary derived growth hormone or ...., promoting the endocrine release from the liver of Insulin, directly stimulates proliferation of chondrocytes
Somatotrin
48
Cell's cartilage can give a benign or slow growing
Chondroma
49
Consist of collagen type I fibers and fibroblast, except in the articular cartilage of joints, all Hyaline cartilage is covered by dense connective tissue
Perichondrium
50
Contains elastic fibers in addition to collagen type II giving a yellowish color
Elastic cartilage
51
Usually requires stains such as
Orcein or resorcin fuchsin
52
Locations of elastic cartilage
Auricle of the ear Wall of the auditory external canals The auditory (eustaquio) tubes The epiglotis
53
Combinations of Hyaline cartilage and dense connective tissue
Fibrocartilage
54
Locations of fibrocartilage
Intervertebral discs Attachment of certain ligaments Pubic symphysis
55
Chondrocytes of fibrocartilage occurs in aligned isogenous aggregates producing matrix containing type
II collagen
56
Components of intervertebral disc
Annulus fibrosus and nucleus pulposus
57
Rich in bundles of type I collagen
Annulus fibrosus
58
Gel like matrix rich in Hyaluronic acid
Nucleus pulposus
59
All cartilage forms from embryonic mesenchyme in the process of
Chondrogenesis
60
Resulting from the mitotic division of preexisting chondroblast
Interstitial growth
61
Involves differentiation of new chondroblast from the Perichondrium
Appositional growth
62
Hyaline cartilage is susceptible to...., during aging
Calcification