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Histologia Junqueira's > Cartilage > Flashcards

Cartilage Flashcards

1
Q

actuando como molde para casi todos los huesos adultos proceso llamado

A

Osificacion endocondral

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2
Q

Envoltura de TC fibroso ricamente vascularizado , que rodea por completo al cartílago a excepción del plano de fricción del cartílago articular y parenquima de tejido cartilaginoso, denominado

A

Pericondrio

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3
Q

Capas del Pericondrio

A

Una externa o fibrosa y celular o interna

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4
Q

Características de capa externa o fibrosa del Pericondrio

A

Abundantes fibras de colageno, venas y arteriolas

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5
Q

Características de capa interna o celular de Pericondrio

A

Fibroblastos y celulas precursoras de cartílago

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6
Q

Celulas del cartílago

A

Condrocitos

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7
Q

Se encuentran mezclados en matriz de sustancia fundamental y fibras conjuntivas pero carece de vasos sanguíneos

A

Condrocitos

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8
Q

Cartílago es

A

Avascular

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9
Q

Los Condrocitos maduros se encuentran en una matriz aislados llamada

A

Laguna condroide

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10
Q

Celulas grandes y redondeadas con núcleo central y citoplasma abundante , cuyo aspecto varía de basofilos a acidofilos según las células estén en fase de síntesis o reposo

A

Condrocitos

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11
Q

Los Condrocitos proceden de la proliferación y diferenciación de los

A

Condroblastos

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12
Q

Se sitúan en la capa celular mas interna próxima a la matriz del Pericondrio

A

Condroblastos

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13
Q

Los Condroblastos quedan envueltos por matriz y siguen sufriendo mitosis aparecen localizados en una sola laguna o con tabiques de separación

A

Grupos isogenicos

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14
Q

Grupos isogenicos más abundantes en

A

Cartílago inmaduro

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15
Q

Matriz o cápsula basofila próxima a los Condroblastos o Condrocitos

A

Cápsula o matriz territorial

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16
Q

Matriz levemente acidofilas

A

Matriz interterritorial

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17
Q

Dentro de la matriz territorial la parte en contacto con el condrocito se muestra más basofila y es

A

Metacromatica con azul de toluidina

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18
Q

La sustancia fundamental de la matriz es amorfa y rica en proteoglycanos especialmente

A

Condroitin 4 sulfato y condroitin 6 sulfato debido a esto provoca metachromasia

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19
Q

Tipo de fibras de colageno que se pueden encontrar, que se disponen en forma de cestas en la matriz territorial alrededor de los condrocitos y formando haces lineales en la matriz interterritorial

A

II,IX,XI y fibras elásticas

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20
Q

Tres tipos de cartílago

A

Hialino, elástico,fibrocartilago

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21
Q

Matriz extracelular es transparente y lisa como el cristal

A

Cartílago hialino

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22
Q

Contiene fibras de colageno y sustancia fundamental abundante , Condrocitos separados por la matriz

A

Cartílago hialino

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23
Q

Dos variedades de cartílago hialino

A

Cartílago articular y el que forma placas metafisiarias

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24
Q

Forma los planos de fricción de articulaciones moviles(diartrosis) , ausencia de Pericondrio en los puntos de rozamiento

A

Cartílago articular

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25
Q

Se encuentra en constante formación en un extremo y en destrucción y sustitución por tejido óseo en el opuesto

A

Cartílago de crecimiento

26
Q

Fibras de colageno elemento más abundante , Condrocitos dispersos entre las fibras de colageno y en dirección orientadas a los fascículos fibrosos

A

Cartílago fibroso o fibrocartilago

27
Q

Predominio de fibras elásticas dispuestas en placas y sustancia fundamental poco abundante ,Condrocitos amontonados

A

Cartílago elástico

28
Q

Donde se encuentra el cartílago elástico

A

Laringe( epiglotis,cartílagos corniculados y cuneiformes,aritenoides,y sésamo ideo)
Tabique nasal
Pabellón auricular

29
Q

Se puede reconocer por una serie de “cabellos” o “pelusas” rosas o moradas alrededor de los Condrocitos

A

Cartílago elástico

30
Q

Forma el esqueleto fetal y de los individuos neonatos actuando como molde para casi todos los huesos adultos

A

Cartílago

31
Q

The most common form of collagen , the principal collagen type

A

Collagen type II

32
Q

Harbors the cartilage vascular supply and nerves and lymphatic vessels

A

Perichondrium

33
Q

Cartilage more common

34
Q

Location of Hyaline cartilage

A

Respiratory passages( nose, larynx,trachea,bronchi)
Ventral ends Ribs
Epiphyseal plates of long Bones
Articular surfaces

35
Q

A chronic condition commonly in aging , the gradual loss or changed physical properties of Hyaline cartilage that lines the articular ends of Bones in joints

A

Osteoarthritis

36
Q

The dry weight of Hyaline cartilage

A

40% collagen embedded in a firm hydrated gel of proteoglycans and structural glycoproteins

37
Q

Most of the collagen in Hyaline cartilage is

38
Q

Most abundant proteoglycan of Hyaline cartilage with approximately 150 GAGs side chain of chondroitin sulfate and keratan sulfate

39
Q

% of the weight of Hyaline cartilage is water

40
Q

Water bound to GAGs in the proteoglycans constituted

A

60% to 80% of the weight of fresh Hyaline cartilage

41
Q

Important components of cartilage matrix is the structural multiadhesive glycoprotein

A

Chondroitin

42
Q

Chondroitin binds to….., mediating the adherence of chondrocytes to the ECM

A

GAGs,collagen type II, and integrins

43
Q

Surrounding each chondrocytes the ECM is relatively richer in GAGs, often causing these áreas of

A

Territorial matrix

44
Q

Hyaline cartilage cells metabolize glucose by anaerobic glycolysis to produce

A

Lactic acid

45
Q

Transport of water and solutes in the matrix is promoted by the pumping action of intermittent cartilage

A

Compression and decompression

46
Q

The inability of cartilage to regenerate or to be repair may be atributed to

A

Chondrocytes immobility, low metabolic and mitotic rates and avascularity

47
Q

A major regulator of hyaline cartilage growth is pituitary derived growth hormone or …., promoting the endocrine release from the liver of Insulin, directly stimulates proliferation of chondrocytes

A

Somatotrin

48
Q

Cell’s cartilage can give a benign or slow growing

49
Q

Consist of collagen type I fibers and fibroblast, except in the articular cartilage of joints, all Hyaline cartilage is covered by dense connective tissue

A

Perichondrium

50
Q

Contains elastic fibers in addition to collagen type II giving a yellowish color

A

Elastic cartilage

51
Q

Usually requires stains such as

A

Orcein or resorcin fuchsin

52
Q

Locations of elastic cartilage

A

Auricle of the ear
Wall of the auditory external canals
The auditory (eustaquio) tubes
The epiglotis

53
Q

Combinations of Hyaline cartilage and dense connective tissue

A

Fibrocartilage

54
Q

Locations of fibrocartilage

A

Intervertebral discs
Attachment of certain ligaments
Pubic symphysis

55
Q

Chondrocytes of fibrocartilage occurs in aligned isogenous aggregates producing matrix containing type

A

II collagen

56
Q

Components of intervertebral disc

A

Annulus fibrosus and nucleus pulposus

57
Q

Rich in bundles of type I collagen

A

Annulus fibrosus

58
Q

Gel like matrix rich in Hyaluronic acid

A

Nucleus pulposus

59
Q

All cartilage forms from embryonic mesenchyme in the process of

A

Chondrogenesis

60
Q

Resulting from the mitotic division of preexisting chondroblast

A

Interstitial growth

61
Q

Involves differentiation of new chondroblast from the Perichondrium

A

Appositional growth

62
Q

Hyaline cartilage is susceptible to…., during aging

A

Calcification

Histologia Junqueira's (24 decks)

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