Cardio Random Flashcards
truncus arteriosus
ascending aorta and pulmonary trunk
bulbus cordis
smooth part of ventricles
primitive atrium
trabeculated portion
primitive ventricle
trabeculated portion
left horn sinus venosus
coronary sinus
right horn sinus venosus
smooth part of right atrium
cardiac looping
begins at week 4
defective in Karagener syndrome
patent foramen ovale
failure of septum primum and septum secundum to fuse
ventricular septal defect
most common congenital cardiac anomaly
most common membranous septum
outflow tract formation
neural crest and endocardial migrate
failure of neural crest cells to migrate
transposition of great vessels
tetralogy of fallot
persistent truncus arteriosus
ductus venosus
into IVC bypassing hepatic circulation
deoxygenated blood in fetal circulation
through ductus arteriosus
oxygenated blood in fetal circulation
through foramen ovale
allantois
urachus becomes median umbilical ligament
umbilical arteries
medial umbilical ligaments
umbilical vein
ligamentum teres hepatis
contained in falciform ligament
SA and AV blood supply
RCA
LCX supply
lateral and posterior walls of left ventricle
LAD supply
anterior 2/3 of interventricular septum
PDA supply
AV node
left dominant from LCX
right dominant from RCA
enlargement RA
dysphagia and hoarseness
pericardial cavity
between parietal and visceral layers
innervation pericardium
phrenic
referred pain to shoulder
pulse pressure relationships
direct to SV
inverse to arterial compliance
decrease pulse pressure
aortic stenosis, cardiogenic shock, cardiac tamponade, HF
increase SV
contractility and preloard increased
decreased afterload
contractility decreases
beta blocker HF systolic dysfunction acidosis hypoxia non-dihydropyridine Ca channel blockers
increase myocardial oxygen demand
contractility
afterload
HR
diameter of ventricle
decrease preload
venous vasodilators
decrease afterload
arterial vasodilators
compensation increase afterload
hypertrophy of LV
most TPR
arterioles
inotropy
contractility
increased catecholamines, digoxin
decreased HF, NO
only alters CO
venous return
changes volume
fluid infusion, sympathetic increase
hemorrhage and spinal anesthesia decrease
TPR
vasopressors increase (and decrease both lines) exercise and AV shunt decreases (increases both lines)
S3
early diastole
increased filling pressures and dilated ventricles
S4
late diastole (atrial kick) lateral decubitus, ventricular noncompliance
a wave
atrail contraction
c wave
RV contraction
x descent
relaxation
v wave
filling against closed valve
y descent
RA emptying into RV
prominent in pericarditis, absent in tamponade
pathologic splitting
inspiration increase VR
delayed closure of pulmonic valve
wide splitting
delayed RV emptying
fixed splitting
in ASD
paradoxical splitting
delay in aortic closure (aortic steonisis, LBBB)
P2 before A2
increase HCOM murmur
valsalva, standing up
MVP and HCOM differ from the others
pulsus parvus et tardus
aortic stenosis
midsystolic click
due to sudden tensing of chordae tendinae
causes aortic regurg
aortic root dilation, bicuspid aortic valve, endocarditis, rheumatic fever
decreased rate of diastolic depolarization
Ach and adenosine
impacts funny current
pacemaker rates
SA>AV
speed of conduction
purkinje>atrai>ventricles>AV
treatment long QT
magnesium sulfate
Romano-Ward syndrome
AD long QT
pure cardiac
Jervell and Lange-Nielsen
AR
sensorineural deafness
Brugada
AD
pseudo-RBB block and ST elevations V1-V3
risk of WPW
reentry circuit
supraventricular tachycardia
Mobitz I
progressive lengthening
Third degree block
associated with Lyme disease
beat independently
aldosterone escape mechanism
ANP
BNP
longer half life
from incrased tension
carotid massage
increase pressure and stretch
increase firing to decrease HR
carotid transmission
via glossopharygneal
aortic transmission
via vagus
Cushing reflex
hypertension, bradycardia and respiratory depression
cerebral ischemia increase pCO2, hypertension, baroreceptors induced bradycardia
central chemoreceptors
pH and PCO2
pulmonary wedge in mitral stenosis
PCWP>LV end diastolic pressure
heart autoregulation
adenosine, NO, CO2, decrease O2
skeletal regualtion
lactate, adenosine, K, H, CO2
boot shaped heart
tetralogy of Fallot
tet spells
increase SVR to improve cyanosis
Ebstein anomaly
displacement of tricuspid leaflets downard into RV
tricuspid regurg and right HF
early cyanosis
R to left shunts
ASD vs PFO
missing tissue in ASD
Eisenmenger syndrome
uncorrected L to R
pulmonary arterial hypertension, RVH
causes late cyanosis, clubbing, polycythemia
complications coarctation of aorta
HF, increased cerebral hemorrhage, aortic rupture, possible endocarditis
diabetic mother
transposition of great vessels
Williams syndrome
supravalvular aortic stenosis
xanthomas
lipid-laden histiocytes
Mockenberg sclerosis
calcification of internal elastic lamina and media of arteries
intima not involved-no obstruction to blood flow
cystic medial degeneration
leads to thoracic aortic aneurysm
HTN, bicuspid aortic valve, Marfan
obliterative endartertitis of vasa vasorum
tertiary syphilis
most common site traumatic aortic rupture
aortic isthmus-proximal descending aorta distal to left subcalvian artery
stanford A aortic dissection
ascending aorta
results in aortic regurg or cardiac tamponade
stanford B
below ligamentum arteriosum
coronary steal syndrome
vasodilators dilates normal vessels and shunts toward well-perfused areas
diverts away from stenosed and ischemic
diagnosis reinfarction
CK-MB
returns to normal after 48 hrs
lateral leads
LCX
I and aVL
inferior leads
RCA
II, III, aVF
papillary muscle rupture
from posterior descending
mitral regurg
Dressler
autoimmune resulting in fibrinous pericarditis
findings dilated cardiomyopathy
HF, S3, systolic regurg
Takotsubo cardiomyopathy
ventricular apial ballooning
associated with HCOM
Fridreich ataxia
findings hypertrophic
S4, mitral regurg
causes restrictive cardiomyopathy
postradiation, Loffler, endocardial fibroelastosis, amyloidosis, sarcoidosis, hemochromatosis
sepsis shock
increase CO, decrease SVR
warm skin
culture negative endocarditis
HACEK
tricuspid endocarditis
staph, pseudomonas, candida
Aschoff bodies
granulomas with giant cells
Anitschkow cells
enlarged macrophages with ovoid, wavy rod-like nucleus
Beck triad
hypotension, distended neck veins, distant heart sounds
pulsus paradoxus
decrease in amplitude >10mm during inspiration
seen in cardiac tamponade, asthma, obstructive sleep apnea, pericarditis, croup
electrical alternans
cardiac tamponade
histology myxoma
gelatinous material, myxoma cells immersed in glycosaminoglycans
association rhabdomyomas
tuberous sclerosis
Kussmaul sign
increase JVP on inspiration
seen in constrictive pericarditis, restrictive cardiomyopathies, RA or RV tumors
association giant cell arteritis
polymyalgia rheumatica
histology PAN
transmural inflammation of arterial wall with fibrinoid necrosis
different stages of inflammation
histology Buerger disease
segmental thrombosing vasculitis
histology granulomatosis
focal necrotizing vasculitis
necrotizing granulomas
necrotizing glomerulonephritis
nodular densities on CXR
histology Churg-Strauss
granulomatous, necrotizing vasculitis with eosinophilia
Hereditary hemorrhagic telangiectasia
blanching skin lesions, epistaxis, AV malformations
use nimodipine
subarachnoid hemorrhage
hydralazines
increase cGMP
lupus like syndrome
caution pindolol and acebutolol
use caution in angina
partial beta-agonists
ranolazine
inhibits late sodium, reducing oxygen consumption
leads to QT prolongation
milrinone
PDE-3 inhibitor inotropic and chronotropic
decrease triglycerides
fibrates
decrease LDL
statins
statin myopathy
particularly when with fibrates or niacin
prevent intestinal reabsoprtion
bile acid resins
cholesterol gallstones
fibrates
adenosine
increase K out of cell
blunted by theophylline and caffeine
ivabradine
inhibition of funny sodium channels
reduces cardiac O2 requirement
adverse ivabradine
visual brightness, hypertension, bradycardia