Carbohydrates 3

Question 1

Glycolysis

Answer 1

Catabolic pathway that saves some potential energy from glucose/G-6-P by forming ATP though substrate level phosphorylation

Question 2

Where does glycolysis take place?

Answer 2

Cytoplasm

Question 3

How many steps are there in glycolysis?

Answer 3

10

Question 4

What are the enzymes involved in glycolysis?

Answer 4

• Hexokinase
• Phosphohexose isomerase
• Phosofructokinase 1
• Aldolase
• Triphosphate isomerase
• Glyderaldehyde phosphate dehydrogenase
• Phosphoglycerate kinase
• Phoshogycerate mutase
• Enolase
• Pyruvate kinase

Question 5

What is the first committed step of glycolysis?

Answer 5

Phosphorylation of F-6-P to F-1,6-bisP

Question 6

What does substrate level require?

Answer 6

Enzymes and chemical intermediates

Question 7

What does respiration linked involve?

Answer 7

Membrane bound enzymes and gradients of protons

Question 8

Where does NAD come from?

Answer 8

Essential vitamin niacin

Question 9

Why does NAD need to regenerated?

Answer 9

• No NAD= no glycolysis

- NAD is limited in the cell

Question 10

What are the fates of pyruvate?

Answer 10

Converted to:

• Ethanol in yeast
• Lactate
• Co2 and water via citric acid cycle

Question 11

What happens when we sprint?

Answer 11

• Our muscles don’t receive O2 fast enough to make ATP via oxidative phosphorylation
• Instead ATP is made via substrate-level phosphorylation producing lactate

Question 12

What is the Cori cycle?

Answer 12

Interaction between the liver and muscle where lactate is converted to Glc in the liver by gluconeogenesis and the liver repays the oxygen debt.