Autonomic Physiology 2 Flashcards
What are responses dependent on?
Neurotransmitter released
Receptor type
Sympathetic: Ciliary muscle relaxes and eye focuses far away
B2
Ciliary muscle round lens
Sympathetic: Radial muscle contracts and makes pupil larger
a1
Radial muscle of iris
Parasympathetic: Ciliary muscle contracts and eye focuses close up
Muscarinic
Ciliary muscle
Parasympathetic: Contracts sphincter muscle and makes pupil smaller
Muscarinic
Sphincter muscle
Sympathetic: Increases heart rate
B1
Pacemaker cells
Sympathetic: Increases strength of contraction
B1
Myocytes
Parasympathetic: Decreases heart rate
Muscarinic
Pacemaker cells
Sympathetic: Makes smooth muscle relax and dilates airways
B2
Smooth muscle of airway
Parasympathetic: Makes smooth muscle contract and constricts airways
Muscarinic
Smooth muscle of airways
Salbutamol
B2 agonist
Dilates airways but does not affect the heart
Atenolol
B1 antagonist
Decreases heart rate but does not affect the airway
Sympathetic: Smooth muscle contract and blood flow decreases
a1
Smooth muscle of vessels
Sympathetic: Makes smooth muscle relax and blood flow increases
B2
Smooth muscle of vessels
Sympathetic: Decreases gut motility
a/B
Smooth muscle of gut
Sympathetic: Inhibits secretion of enzymes
a
Pancreas
Parasympathetic: Increases gut motility
Muscarinic
Smooth muscle of gut
Parasympathetic: Increases secretion in the gut
Muscarinic
Pancreas
Sympathetic: Stimulates glycogenolysis and gluconeogenesis
a/B
Hepatocytes
Sympathetic: Increases lipolysis
a/B
Lipocytes
Sympathetic: Stimulates thick secretion rich in enzymes
B
Salivary glands
Parasympathetic: Stimulates profuse watery secretion
Muscarinic
Salivary glands
Sympathetic: Relaxes smooth muscle and reduces pressure
B2
Smooth muscle of bladder wall
Sympathetic: Contracts smooth muscle and stops urination
a1
Smooth muscle of sphincter
Parasympathetic: Contracts smooth muscle and increases pressure
Muscarinic
Bladder wall
Parasympathetic: Relaxes smooth muscle and causes urination
Muscarinic
Sphincter
Sympathetic: Contracts smooth muscle and causes ejaculation
a1 Smooth muscle of urethra
Parasympathetic: Relaxes smooth muscle and causes erection
Muscarinic
Smooth muscle of corpus cavernosum
What controls all of these responses?
Autonomic reflexes and central control
What complications may there be?
Neurones may co-release transmitters e.g ACg plus a peptie