Brucella Flashcards

1
Q

Among the Brucella species Brucella melilentis is the most pathogenic species for humans

A

T

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2
Q

Brucella species cannot tolerate high temperature (60 °C) and low pH (pH: 4).

A

T
-resistance medium

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3
Q

Rose-Bengal test is used for the detection of antibodies against brucellae

A

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4
Q

Brucellae can be detected by staining in the placenta of aborted foetuses in the case of brucellosis

A

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5
Q

Humans can acquire brucellosis from raw milk

A

T

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6
Q

Europe is free from Brucella ovis

A

F

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7
Q

Undulant fever, malaise, inappetence, fatigue, and muscle and joint pains can be the clinical sings of human brucellosis

A

T

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8
Q

Brucella species are generally zoonotic agents

A

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9
Q

Brucella are facultative IC agents

A

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10
Q

Brucella is generally a notifiable disease

A

T

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11
Q

More than one serological test must be carried out from one serum sample at the same time in the case of serodiagnostics of brucellosis

A

T

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12
Q

Brucellosis is a chronic disease

A

T

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13
Q

Brucella species are gram-negative, fastidious, coccoid rod-shaped bacteria

A

T

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14
Q

There is a serological relationship among some brucella species, because of the same polysaccharides in the cell wall

A

T

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15
Q

Worldwide distribution is characteristic for brucellosis

A

T?
-Endemic in Mediterranean Malta fever?

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16
Q

Köster staining is used for staining of brucellae

A

T

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17
Q

Brucella can be both acute or chronic in humans

A

T

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18
Q

Brucella melitensis is endemic in Mediterranean area

A

T

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19
Q

Brucella species are serologically uniform

A

F

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20
Q

Brucella species need cysteine or cystine as an additive for the culture

A

F

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21
Q

Brucella species are not zoonotic agents

A

F

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22
Q

Susceptibility of humans to different Brucella species is different

A

T

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23
Q

Consumption of raw milk is an important route of human Brucella infection

A

T

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24
Q

Brucella need chocolate agar to culture

A

F

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25
Q

There is a close antigenic relationship between B. ovis and B. melitensis

A

F

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26
Q

B. suis is a zoonotic agent

A

T

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27
Q

Brucella ovis needs CO2 to culture

A

T
-obligate aerobic capnophilic?

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28
Q

Brucella are Gram-positive and Köster-positive bacteria

A

F

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29
Q

The antigens of Brucella are uniform

A

F

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30
Q

The majority of the Brucella species can infect humans

A

T

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31
Q

Brucella are not fastidious bacteria, they can be cultured on simple nutrient agar

A

F

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32
Q

Brucella species are non-motile, Gram-negative, small coccoid rods

A

T

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33
Q

There is a serological relationship among B. abortus, B. melitensis and B. ovis, because of the same surface polysaccharides

A

F

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34
Q

There are no brucellosis-free countries in the world

A

F

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35
Q

There is close antigenic relationship between Brucella bovis and Brucella ovis

A

F-no brucella bovis

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36
Q

Brucella canis is stained red as a result of Köster-staining

A

F

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37
Q

Brucella species are not fastidious bacteria, we can use nutrient agar in diagnostic work

A

F

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38
Q

There is a strong relationship in antigenic structure of Brucella canis and Brucella ovis

A

T

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39
Q

Fetus, fetal membrane and blood sample from the dam must be send to the diagnostic institute in abortion case

A

T

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40
Q

Human brucellosis was described for the first time by David Bruce in Malta Island in 1886

A

T

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41
Q

Brucella abortus stains red as a result of Köster-staining

A

T

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42
Q

There is a strong relationship in the antigenic structure of B. melitensis and B. suis

A

T

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43
Q

All of the Brucella species are zoonotic agents

A

F

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44
Q

Vaccination is a regularly used prevention method in the brucellosis free countries of EU

A

F

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45
Q

In the case of a same serum sample it is advisable to carry out more serological tests for the detection of antibodies against Brucella species, because different serological tests can show different results

A

T

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46
Q

Rev I. is an inactivated vaccine strain

A

F

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47
Q

There are no differences in serological features of Brucella species with veterinary importance

A

F

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48
Q

With Köster-staining all Brucella are positive

A

F

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49
Q

Sheep and goat are the reservoirs for Brucella

A

F

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50
Q

Hungary is Brucella free

A

F

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51
Q

Humans are resistant to Brucella melitensis

A

F

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52
Q

Raw milk consumption can be the source of human brucellosis

A

T

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53
Q

Vaccination against brucellosis is common in the EU

A

T

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54
Q

Attenuated vaccine strains can cause abortion in pregnant animals

A

T

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55
Q

Focal necrosis and inflammation are seen in fetuses aborted due to Brucella

A

T

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56
Q

Brucella is an obligate pathogen

A

T
F?

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57
Q

Brucella are a notifiable disease

A

T

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58
Q

Brucella can be found on the mucous membranes of the genital tract

A

T

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59
Q

All Brucella can be stained with Köster staining

A

F

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60
Q

There will be cross-reactions between S-type colonies in case of Brucella

A

T

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61
Q

Brucellosis is found in most parts of the world

A

T

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62
Q

In sexually immature animals, Brucella multiplies in the lymph nodes

A

T

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63
Q

Brucellosis is usually introduced by infected asymptomatic animals

A

T

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64
Q

Abortion caused by brucellosis is followed by retained fetal membranes

A

T

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65
Q

An attenuated vaccine is used in Hungary for prevention of B. melitensis

A

F

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66
Q

Brucella has average resistance

A

T

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67
Q

Brucella is seen only in the northern hemisphere

A

F

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68
Q

Herd replacement is the only way of eradication of porcine brucellosis

A

T

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69
Q

Wild boars and wild hares can serve as reservoir species of swine brucellosis

A

T

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70
Q

Wild boars can be the carrier of Brucella melitensis

A

F

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71
Q

Worldwide occurrence is characteristic for swine brucellosis

A

T

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72
Q

Brucella suis can cause chronic localized udder infection in cattle

A

T

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73
Q

Brucella suis can infect only pigs

A

F

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74
Q

Wild boars can infect domesticated pigs with Brucella suis

A

T

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75
Q

Brucella suis serological tests can be used for livestock diagnosis only

A

T

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76
Q

Brucella suis can colonise the udder of cattle

A

T

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77
Q

Osteomyelitis is a frequent sign of porcine brucellosis

A

T

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78
Q

Brucella suis causes Swine Brucellosis

A

T

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79
Q

Wild boars can be the source of swine brucellosis in domestic pigs reared outdoors

A

T

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80
Q

European brown hare can carry and shed B. suis biotype 2

A

T

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81
Q

Swine brucellosis does not occur in Europe

A

F

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82
Q

Rev-1 strain is an attenuated live B. suis strain

A

F

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83
Q

B. suis can infect brown hares

A

T

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84
Q

Brucella suis can cause severe abortion in cattle

A

F

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85
Q

Brucella bovis can infect brown hares

A

F

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86
Q

Arthritis is a typical clinical sign of porcine brucellosis

A

T

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87
Q

Farmed pigs are regularly vaccinated against brucellosis in Europe in order to prevent infection from wild boars

A

F

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88
Q

Stock exchange is the only safe eradication method in case of swine brucellosis

A

T

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89
Q

Swine brucellosis is an exotic disease in Europe, we can see this disease in South-East Asia only

A

F

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90
Q

In swine brucellosis the results of serological tests can be used only for herd diagnosis, because the low sensitivity and specificity of these serological tests

A

T

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91
Q

Pneumonia and nasal discharge are characteristic clinical findings in swine brucellosis

A

F

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92
Q

B. suis biotype 2 is widespread in wild swine population all over the world

A

T

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93
Q

Swine brucellosis can be treated successfully with antibiotics

A

F

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94
Q

Porcine brucellosis is a notifiable disease

A

T

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95
Q

With the help of the appropriate antibiotics we can eradicate B. suis from a swine herd

A

F

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96
Q

Humans are not susceptible to the causative agent of swine brucellosis

A

F

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97
Q

Wild hare is an important reservoir of Brucella abortus biotype 2 in Europe

A

T

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98
Q

Brucella suis was isolated by Sir David Bruce as a first time in 1886 in Malta Island

A

F

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99
Q

Brucella suis biotype 2 can cause disease in hares

A

T

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100
Q

In the case of swine brucellosis, no clinical signs can be seen in boars

A

F

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101
Q

Stock exchange in the main way of eradication of porcine brucellosis

A

T

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102
Q

Swine brucellosis is present in wild boars in several European countries

A

T

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103
Q

Hungary is free from Brucella suis

A

F

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104
Q

Secondary hosts of swine brucellosis are dog, human and cattle

A

T

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105
Q

Maintaining host of swine brucellosis are reindeer, hare and small rodents

A

F

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106
Q

Brucellosis in swine causes abortion at any time of the pregnancy

A

T

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107
Q

Boars are asymptomatic in case of brucellosis infection

A

F

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108
Q

Abortion occurs due to liver lesions in the piglets in case of brucellosis

A

F

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109
Q

Chronic cases of brucellosis cause lameness in both boars and sows

A

T

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110
Q

Antibiotics are widely used to treat swine brucellosis

A

F

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111
Q

Abortion is a frequent clinical sign of porcine brucellosis

A

T

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112
Q

Stillbirth is a frequent clinical sign of porcine brucellosis

A

T

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113
Q

Diarrhoea is a frequent clinical sign of porcine brucellosis

A

F

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114
Q

Brucella abortus can cause septicaemia in cattle

A

T

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115
Q

Brucella abortus can cause necrosis in the chorionic villi of pregnant cattle

A

T

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116
Q

ABR test can detect antibodies against Brucella abortus in milk

A

T

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117
Q

Arthritis is a clinical sign of bovine brucellosis

A

T

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118
Q

Fluoroquinolones are the first choice for treatment of bovine brucellosis

A

F

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119
Q

In case of brucellosis our aim is eradication and maintain the disease-free status

A

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120
Q

Abortion is a clinical sign of bovine brucellosis

A

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121
Q

Brucella abortus can colonise the udder and shed with the milk of cows

A

T

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122
Q

Brucella abortus can colonise the testicles, epididymis and accessory genital glands and shed with the semen

A

T

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123
Q

Cattle can be asymptomatic carriers of brucellae

A

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124
Q

Infected cattle carry brucellae lifelong

A

T

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125
Q

Calves can be infected with brucellae during pregnancy if the cow is infected

A

F

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126
Q

Bovine brucellosis is caused by Brucella bovis

127
Q

Brucella melitensis can cause abortion in cattle

128
Q

Antibacterial treatment is pointless in bovine brucellosis

129
Q

Brucella abortus can colonise only pregnant cows or heifers

130
Q

Brucella abortus can cause abortion of cattle

131
Q

Brucella abortus and brucella melitensis can cause bovine brucellosis

132
Q

Bovine brucellosis has to be treated 4-6 weeks long with penicillins

133
Q

Brucella abortus can colonise only cattle

134
Q

Cattle cannot infect humans with Brucellae

135
Q

The maintaining host of Bruecella abortus is the goat and the sheep

136
Q

Orchitis is a clinical sign of Bovine Brucellosis

137
Q

Calves can be born with Brucella

138
Q

Brucellosis of cattle is mainly limited to the genital tract

139
Q

In the case of bovine brucellosis abortion usually occurs after fifth month of gestation

140
Q

Retention of fetal membranes is a characteristic clinical sign of bovine brucellosis

141
Q

Brucellosis caused by Brucella melitensis occurs in the Mediterranean area

142
Q

The S19 strain is an inactivated B. melitensis strain, which can be used for brucellosis

143
Q

Nervous clinical signs are frequent in the case of bovine brucellosis

144
Q

Bovine brucellosis can be diagnosed using the tuberculin test

145
Q

ABR test cannot be used to test colostrum

146
Q

Bovine brucellosis is a self-limiting disease

147
Q

Bovine brucellosis was described for the first time by Sir David Bruce in 1886

148
Q

Bovine brucellosis is not a notifiable disease

149
Q

Rose-Bengal test is a frequently used serological test in the diagnostic work of brucellosis

150
Q

In ABR (Abortus bang ring/Brucella milk ring) test, we detect brucella antigens in the milk

151
Q

Fluoroquinolone treatment can cease shedding of Brucella

152
Q

Rev 1. strain is a modified live vaccine strain of B. melitensis

153
Q

Sensitivity and specificity of the serological tests, which are used in Brucella diagnostics are different

154
Q

Bovine brucellosis is a notifiable disease

155
Q

An early antibiotic therapy is really important in the treatment of bovine brucellosis

156
Q

Brucella abortus can cause an abortion storm in a newly infected pregnant cattle herd

157
Q

In case of bovine abortion we must send only fetal fluid to the diagnostic laboratory, because is enough for the diagnosis

158
Q

In the ABR test we detect Brucella abortus bacteria in the cattle milk

159
Q

S19 vaccine is a live vaccine, which can cause abortion in pregnant cows

160
Q

Serological tests are frequently used methods in the diagnosis of bovine brucellosis

161
Q

False positive or false negative reactions can be seen in the serological tests in the serodiagnostics brucellosis

162
Q

Icterus is a frequently seen clinical signs of bovine brucellosis

163
Q

ABR test is a human serological test for the detection of antibodies in human blood serum sample

164
Q

Most important clinical sings of bovine brucellosis are icterus and CNS signs

165
Q

Cattle are generally infected with Brucella per os

166
Q

After infection brucella replicate in the lymph nodes of cattle

167
Q

Bulls are resistant to Brucella infection

168
Q

Bovine brucellosis is always an acute disease

169
Q

Bovine brucellosis is widespread within the EU

170
Q

Necrosis of fetal membrane is a post mortem lesion of bovine brucellosis

171
Q

Brucella can be detected in fetal membrane and fetus with Köster staining

172
Q

Infected cattle can be recognized by detecting Brucella in blood with ELISA

173
Q

ABR test is used to detect Brucella in milk

174
Q

Brucella abortus causes no disease in bulls

175
Q

Brucella are introduced in a herd with infected animals

176
Q

Brucella colonize the lymph nodes in young calves

177
Q

Brucella abortus can colonize only cattle

178
Q

Cattle are mainly infected with Brucella sexually

179
Q

Brucellosis of cattle is mainly limited to the genital tract only

180
Q

Brucella abortus can be carried and shed by dogs and cats

181
Q

Brucella abortus can cause abortion wave in a cattle herd, when it is newly introduced

182
Q

Fetus, fetal membranes and blood sample of the cow have to be sent to the diagnostic institute in case of abortions

183
Q

Antibodies against Brucella abortus are detected in the ABR test

184
Q

Male calves may be vaccinated with vaccines containing live attenuated strains, without any side effects

185
Q

Rev-1. vaccine can cause abortion of pregnant animals

186
Q

Brucellosis of bovine cannot be shed in the milk

187
Q

B. suis can infect cattle.

188
Q

Brucellosis can cause placentitis in cattle

189
Q

In case of brucellosis in cattle, only very few bacteria are needed to cause the disease

190
Q

Bovine brucellosis is primarily caused by venereal infection

191
Q

Calves shows clinical sign after weaning when infected young with brucellosis

192
Q

B. abortus can cause bovine brucellosis

193
Q

B. melitensis can cause brucellosis in cattle

194
Q

Bovine brucellosis is seen in most European countries

195
Q

Bovine brucellosis is zoonotic

196
Q

If young calves are infected with brucellosis, the bacteria remain in the lymph nodes until maturity

197
Q

In the case of bovine brucellosis, septicemia happens

198
Q

Cattle recovered from brucellosis do not remain carriers

199
Q

Bovine brucellosis is only endemic in Hungary

200
Q

The biggest economic damage to bovine brucellosis is orchitis in bulls

201
Q

Histophilus somni and Actinobacillus seminis can cause similar lesions in the genitals of rams as Brucella ovis

202
Q

Brucella ovis infection is restricted to urogenital organs

203
Q

Brucella ovis can cause an acute abortion outbreak in a cattle herd

204
Q

Brucella ovis can cause septicaemia in cattle

205
Q

Brucella ovis can infect humans

206
Q

Brucella ovis occurs in most sheep-raising regions of the world

207
Q

Wild hares can be the carrier of Brucella ovis

208
Q

Brucella ovis mainly causes abortion, clinical signs in males are rare

A

F-
the other way

209
Q

Brucella ovis is shed in semen

210
Q

Brucella ovis and B. canis are koster-negative

211
Q

Agar gel diffusion test and ELISA are used for the detection of infection with Brucella ovis

212
Q

It is possible to eradicate brucella ovis from infected rams using antibacterial drugs

213
Q

Brucella ovis is a zoonotic agent

214
Q

The most frequently seen clinical sign of B. ovis infection is abortion of ewes

215
Q

Humans can be infected with Brucella ovis from raw sheep or goat milk, are common clinical signs of the disease

216
Q

Ovine brucellosis caused by B. ovis is zoonosis

217
Q

The Rev-I vaccine strain is an attenuated, live B. ovis strain

218
Q

Brucella ovis can cause epididymitis and orchitis also in men

219
Q

Brucella ovis has been eradicated from Europe

220
Q

Only sheep is susceptible to Brucella ovis infection

221
Q

Brucella ovis can cause ascending infection of the genital tract

222
Q

Orchitis and epididymitis are the main clinical signs caused by Brucella ovis

223
Q

Sheep, goats, cattle are susceptible for Brucella ovis

224
Q

Brucella ovis causes in rams orchitis and epididymitis

225
Q

Rams are lifelong carriers of Brucella ovis

226
Q

Sometimes abortion can be seen in the case of brucellosis of sheep caused by B. ovis

227
Q

Brucellosis of sheep caused by B. ovis is generally treated with tetracyclines

228
Q

Infectious epididymitis is caused by B. ovis

229
Q

B. ovis has a wide host range

230
Q

Brucellosis in sheep is introduced to the herd by infected asymptomatic rams

231
Q

B. ovis can cause abortion in ewes

232
Q

B. ovis will cause high fever

233
Q

B. ovis causes severe epididymitis

234
Q

You can get B. ovis free only with stock exchange

A

F-
test and remove

235
Q

Ewes are lifelong carriers of Brucella ovis

236
Q

Humans are very susceptible to B. ovis

237
Q

The best way of controlling brucellosis in sheep is eradication of infected rams

238
Q

There is no B. ovis in Hungary

239
Q

Brucella ovis generally does not cause septicaemia in rams

240
Q

Humans can be infected with Brucella ovis from raw sheep and goat milk

241
Q

AGID can be used to diagnose brucellosis in sheep

242
Q

The maintenance host of Brucella abortus is he goat and the sheep

243
Q

Brucella melitensis infection of sheep and goat is common in Mediterranean littoral

244
Q

B. melitensis can disappear spontaneously from sheep and goat

245
Q

Herd replacement is the only method of eradication of B. melitensis in a goat herd

246
Q

Brucella melitensis is an obligate pathogenic bacterium in sheep and goat

247
Q

Brucella melitensis can infection only goats and sheep

248
Q

Brucella melitensis is endemic in the Mediterranean area

249
Q

Brucella melitensis can cause orchitis and epididymitis in rams and bucks

250
Q

Diseases caused by Brucella melitensis can be prevented with vaccination

A

T-rev1 live

251
Q

B. melitensis infection is common in most EU countries

252
Q

B. melitensis can cause orchitis in rams

253
Q

There are vaccines for prevention of B. melitensis

254
Q

Brucella melitensis is sporadic in Hungary

255
Q

Sheep and goats can be infected per os with Brucella melitensis

256
Q

Brucella melitensis causes abortion in goats and sheep

257
Q

Brucella melitensis can be prevented by attenuated vaccines

258
Q

Self-limiting nature of brucellosis caused by Brucella melitensis is strong

259
Q

Brucella melitensis can infect only goats

260
Q

Antibodies against Brucella melitensis can be detected in small ruminants all over Europe

261
Q

B. melitensis is mostly affecting the northern part of Europe

262
Q

Humans are highly susceptible to B. melitensis

263
Q

B. melitensis brucellosis is strongly self-limiting

264
Q

Rev-1 is an attenuated B. melitensis vaccine

265
Q

Goats and sheep are primary hosts of B. melitensis

266
Q

Caprine brucellosis cannot be prevented with vaccination

267
Q

Caprine brucellosis is caused by B. ovis

268
Q

Caprine brucellosis is endemic in the Mediterranean area

269
Q

Rams are asymptomatic in case of brucellosis

270
Q

Primary way of infection of B. melitensis is by mating

271
Q

B. melitensis shed in the fetus, milk and semen

272
Q

B. melitensis occurs sporadically in sheep flocks in Hungary

273
Q

In abortion caused by B. melitensis, inflammatory necrotic foci are seen in the placenta

274
Q

Brucella canis cannot cause abortion in dogs, it causes only orchitis in males

275
Q

Brucella canis can be isolated from blood of infected dogs for years post infection

276
Q

Brucella suis can infect dogs

277
Q

Brucella canis is the aetiological agent of canine brucellosis

278
Q

Scrotal dermatitis is a characteristic clinical sign of canine brucellosis

279
Q

Dogs and cats can be infected with brucella abortus without any clinical signs

280
Q

Brucella canis is shed in the semen

281
Q

Brucella melitensis can infect dogs

282
Q

Brucella abortus can infect dogs

283
Q

Brucella canis can infect humans

284
Q

Agent of canine brucellosis can infect humans

285
Q

Canine brucellosis does not occur in Europe

286
Q

Dogs and cats can carry and shed different Brucella sp. without any clinical signs

287
Q

Rev I. is a live vaccine strain of B. canis

288
Q

The most important clinical sign of canine brucellosis is abortion of pregnant bitches

289
Q

For the prevention of canine brucellosis vaccination is a frequently used method in Europe

290
Q

Dogs can carry and shed other Brucella species than B. canis, too

291
Q

Hemoculture is a good diagnostic tool in the diagnostic work of canine brucellosis

292
Q

Canine brucellosis is caused by B. canis

293
Q

Abortion due to canine brucellosis occurs in final phase of pregnancy

294
Q

Canine brucellosis has no clinical sign in male dogs

295
Q

In the case of canine brucellosis the agent can be isolated from blood

296
Q

Canine brucellosis is a zoonotic disease

297
Q

Dog and cat can carry and shed Brucella species

298
Q

Canine brucellosis differs from other brucella infections since it’s a long-term active infection

299
Q

Canine brucellosis spread via mating or per os

300
Q

Canine brucellosis can cause iridocyclitis

301
Q

Sheep, foxes and cats are secondary carriers

302
Q

Abortion usually occurs in the late phase of pregnancy in case of canine brucellosis

303
Q

Epididymitis and orchitis are typical clinical signs of canine brucellosis

304
Q

Attenuated vaccines are widely used for the prevention of canine brucellosis

305
Q

Strong self-limitation can be seen in the case of canine brucellosis

306
Q

Horses are infected by goats in case of brucellosis

307
Q

In case of brucellosis, horses suffer from bursitis and they can rupture

308
Q

In case of brucellosis hares can maintain their own infectious cycle, and do not need to be infected by cattle

309
Q

Hares are susceptible to B. abortus

310
Q

Reindeers are important in maintaining and infecting swine herds with B. suis

311
Q

Brucellosis can be acute and chronic in humans

312
Q

High fever is a clinical sign of brucellosis in humans

313
Q

Arthritis is a clinical sign of human brucellosis