Breast Flashcards

1
Q

___________ (off 2nd intercostal nerve) sensation to medial arm; can or cannot sacrifice?

A

Intercostobrachial nerve; CAN sacrifice

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2
Q

_________ nerve to serratus anterior, injury= ______

A

Long thoracic nerve; winged scapula

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3
Q

_______ nerve to latissimus dorsi, injury= ________

A

Thoracodorsal nerve; weak arm adduction/pull ups

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4
Q

_________ nerve to pec major and minor

A

Medial pectoral nerve

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5
Q

______ nerve to pec minor only

A

lateral pectoral nerve

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6
Q

_______: Valveless vertebral veins, allow direct mets to _____

A

Batson’s plexus; mets to spine

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7
Q

Poland syndrome: _______, _______, ______

A

amastia, hypoplastic shoulder, no pectoralis

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8
Q

Mastodynia Rx?
____, ____, ___, ____
____ not useful

A

danazol; OCP; evening primrose oil; tamoxifen (?); vit E not useful

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9
Q

______: thrombophlebitis of superficial vein of breast. Cord like mass laterally; Rx: ______.

A

Mondor’s disease; rx NSAIDs

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10
Q
Breast Cancer T sizes:
T1 \_\_\_\_
T2 \_\_\_\_
T3 \_\_\_\_
T4 \_\_\_\_
A

T1 < 2cm
T2 2-5cm
T3 >5cm
T4 skin or chest wall involvement

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11
Q

breast ca ‘grave signs’ = ______, ______

A

peau d’orange, inflammation

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12
Q

Breast cancer N stuff
N1 ______
N2 ______
N3 ______

A

N1 positive ax nodes
N2 matted or fixed nodes
N3 internal mammary nodes

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13
Q
Breast cancer stages:
Stage I \_\_\_\_
Stage II \_\_\_\_\_ or \_\_\_\_
Stage III \_\_ or \_\_
Stage IV \_\_\_\_
A

I: T1
II: up to T2N1 or T3N0
III: T4 or N2
IV: Mets (includes supraclav node; unlike lung CA)

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14
Q

Breast mets: ___, ____, _____

A

bone, lung, brain

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15
Q

_______: a marker for breast CA, implies worse prognosis. _______ now available for Rx.

A

Her 2 neu; Herceptin

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16
Q

___, ___, ____ all indicate worse prognosis in breast ca

A

erb b 2, p 53, cathepsin

17
Q

1 cm tumor is around how old?

A

~5 year old

18
Q

_______ reduces risk 50% in high risk bu inreases risk of ______ cancer and ____.

A

Tamoxifen; endometrial cancer, DVT

19
Q

_________ raises risk x 4 for breast cancer

A

atypical hyperplasia (only finding in fibrocystic that increases risk)

20
Q

ER +/- PR +/- ____; is better than ER PR __ which is better than ER PR __ which is better than ER PR __

A

ER+PR+ > ER-PR+ > ER+PR- > ER-PR-

21
Q

DCIS ____% develop invasive carcinoma; is or is not a precursor?

A

50%; is a precursor

22
Q

DCIS Rx
usually _____
high grade/large tumor/poor margins _____

A

usually lumpectomy + RT;

mastectomy for high grade, etc.

23
Q

___% of DCIS recurrence is invasive

A

50%

24
Q

LCIS ____% develop invasive carcinoma (either breast)

A

30-40%; is a marker of risk

25
Q

Rx options for LCIS

___, _____, ____

A

nothing, tamoxifen or bilateral mastectomy

26
Q

Comedo breast cancer:
Multicentric or localized? ____
Rx? ____
Good or poor prognosis? ___

A

Multicentric; mastectomy; poor

27
Q

Paget’s disease of the breast:
____ lesions on the ___ (part of breast)
There is underlying ____ or ____

A

eczematous lesions on nipple; underlying DCIS or Ductal Ca

28
Q
Cystosarcoma Phyllodes or 'Phyllodes tumor'
\_\_\_\_% malignant? \_\_\_
Large or small? \_\_\_\_
Rare or common nodal mets? \_\_\_\_
Spread? Heme/lymph \_\_\_\_
A

10% malignant; large; rare nodal mets; hematogenous

29
Q

Rx for cystosarcoma phyllodes or “Phyllodes tumor’

A

wide local excision, rarely mastectomy, NO axillary node dissection

30
Q

BRCA: ___% have cancer by age 70

A

85%

31
Q

BRCA1 a/w ___ cancer (____%)

A

ovarian cancer; 50%

32
Q

BRCA2 a/w ______

A

male breast cancer

33
Q

Indications for RT after mastectomy:
___ nodes
____ involvement
_____

A

> 4 nodes; skin or chest wall involvement; positive margins

34
Q
Stewart Treves: \_\_\_\_\_\_\_\_\_ in \_\_\_\_\_\_\_\_\_\_ limb. Presents with \_\_\_\_\_\_\_ on arm.
Occurs \_\_\_\_\_\_ (time) s/p \_\_\_\_\_\_
A

lymphangiosarcoma in lymphedematous limb; purplish mass on arm; 10 years s/p MRM

35
Q

_____: No risk of CA. #1 cause of bloody nipple discharge (although 1/2 are serous)

A

Intraductal Papilloma