Brain Damage Flashcards

1
Q

edema

A

accumulation of fluid (swelling) can cause pressure on brain areas and compromises function to lead to further damage and further strokes

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2
Q

lacunar stroke

A

ischemic stroke type, caused by blocks of small, penetrating end-branches

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3
Q

stenosis

A

abnormal narrowing of a blood vessel

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4
Q

tPA

A

tissue plaminogen activator - the clot-buster, restores blood flow

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5
Q

solitaire catheter device

A

removes the clot itself

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6
Q

decorticate response to pain

A

abnormal flexion to painful stimuli

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7
Q

decerebrate response to pain

A

extension to painful stimuli (more severe damage than decorticate response)

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8
Q

mTBI mild TBI

A

concussion

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9
Q

mild TBI classification system

A

LOC < 30, PTA < 24h

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10
Q

moderate TBI classification system

A

LOC > 30, PTA >24h

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11
Q

PTA

A

post traumatic amnesia

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12
Q

LOC

A

loss of consciousness

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13
Q

what is TBI defined by? symptoms?

A

NO by course

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14
Q

PCS

A

post concussion syndrome, 1-10% of population present symptoms greater than one year post-injury, but its not specific to concussion or a syndrome (could be due to depression), requires validity measures

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15
Q

severe TBI GCS score

A

< 9

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16
Q

moderate TBI GCS score

A

9-12

17
Q

minor TBI GCS score

A

> =13

18
Q

what are 5 common stroke mechanisms?

A

ischemic:
1) atherosclerosis ischemic (thrombotic stroke)
2) blood clots travel from larger to smaller vessel (embolic stroke)
3) small penetrating end-branches block (lacunar stroke)
hemorrhagic:
4) small aneurysms on penetrating end-arteries or AVM’s leak into brain (intra-cerebral hemorrhagic stroke)
5) large congenital Berry aneurysm of Circle of Willis vessels rupture (sub-arachnoid hemorrhage)

19
Q

thrombosis

A

blockage of vessel

20
Q

embolism

A

clot breaks off and circulates-forms a blockage as the vessel narrows

21
Q

transient ischemic attacks (TIA’s)

A

episode of vascular insufficiency that causes a temporary loss of brain function with total recovery within 24 hours, due to small atheroemboli that subsequently dissolve

22
Q

secondary prevention

A

after TIA or stroke

23
Q

acute treatment of stroke

A

tPA (clot buster)

24
Q

risk factors for stroke

A
  • hypertension (lack of elasticity in vessels)
  • hyperlipidemia
  • diabetes
  • atrial fibrillation
  • ischemic heart disease
  • BP/metabolic syndrome
  • alcoholic heart disease
  • cigarette smoking
25
Q

toxins

A

substances can be toxic to cells and cause cell-death (e.g. CO, illicit drugs, alcohol)