Brain Bee Chapter 13 - Jacey Flashcards
just a few years ago, the brain was thought to be an:
immune privileged organ
why was the brain thought to be a “immune privilege organ”?
because it was not affected by immune responses are inflammation
what is our first line of defence against vicious defenders?
immune system
the immune system triggers _______, _______ and ____ ____ ____ that travel do the site of attack, kill and remove pathogens.
leucocytes, macrophages and acute phase proteins
the brain receives signals from injured or ________ tissues that may be neutral in origin
infected
c-fibres communicate which feeling?
pain
aside from c-fibres, what nerve in the liver communicates pain?
vagus nerve
how are prostaglandins inhibited?
aspirins
cytokines are a group of…
proteins
what is the trigger for cytokine?
bacterial or viral
products, damage to cells or threats to cell survival such as toxins or low levels of oxygen
cytokines are protein molecules with many actions, especially on the _______ system
immune
name a main stress response in the brain
increased CRF production
CRF travels the short distance from the \_\_\_\_\_\_\_\_\_\_\_ to the pituitary gland to release another hormone, adrenocotrophin releasing factor (ACTH).
hypothalamus
Recent research has shown that many of the defence
molecules such as cytokines are also active contributors to brain diseases such as…
multiple sclerosis, stroke, Alzheimer’s.