bone and cartilage Flashcards

1
Q

what is a eurypholus

A

bony fish

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2
Q

what is a hybodus

A

cartilaginous fish

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3
Q

what are the roles of periosteum

A

1 major role in bone formation 2 tendons, ligaments and joint capsules attach to it not directly to bone. 3 carries blood vessels and nerves 4 major role in bone repair post fracture

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4
Q

what is the epiphysis

A

found at the end of a long bone after the diaphysis

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5
Q

what is the diaphysis

A

shaft, cylindrical and narrow

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6
Q

where is the endosteum found

A

lining marrow cavity

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7
Q

what is the bone made up of

A

cancellous/spongy/trabeculae/with spicules

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8
Q

how is a fracture created

A

mineral shears at 45degrees in compression, collagen snaps transversely in tension, torsion creates a helical fracture, bending causes compression and tension on opposite sides

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9
Q

what is a mesenchyme cell

A

undifferentiated fetal connective tissue

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10
Q

what are chrondoblasts and osteoblasts

A

active cells that can lay down membrane cartillage

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11
Q

what are chrondocytes and osteocytes

A

resting in lacunae

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12
Q

what are the functions of bone 9

A

1 struts, 2 levers 3 protects 4 elastic potential energy store 5 acoustic 6 display 7 combat 8 blood cell prod 9 mineral store

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13
Q

describe the features of cartilage

A

firm extracellular chondrin matrix, sulfated mucopolysaccharide gel + network of type 2 (UNUSUAL) collagen fibres

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14
Q

what is cartilage described as

A

reinforced concrete - gel resists tension and fibres resist compression

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15
Q

what is cartilage laid down by

A

chrondoblasts

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16
Q

where are resting chrondrocytes

A

in 2-4 cell colonies in lacunae, no nerves, rarely blood vessels, often surrounded by perichondrium

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17
Q

types of cartilage

A

hyaline skeletal, elastic skeletal, fibrocartilage skeletal, articular and hyaline model precursor

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18
Q

what is hyaline skeletal

A

simplest, may mineralise, found in upper respiratory tract, ventral ribs

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19
Q

what is elastic skeletal

A

contains elastin fibres too as in the external ear, upper respiratory tract

20
Q

what fibrocartilage skeletal

A

alternating layers of hyaline cartilage and collage found in intervertebral discs, scuta, labra, menisci and discs

21
Q

what is articular cartillage

A

complex partly fibrous/ partly hyaline from

22
Q

what is hyaline model precursor

A

for bone development

23
Q

describe the structure of long bones

A

constantly remodelled, yielding many parallel cylinders called OSTEONS

24
Q

what is an osteon made up of

A

concentric cylinders of matrix interspersed with lacunae

25
what does each lacunae contain
a resting osteocyte, they are stellate with radiating tiny canniculi permeating bone containing cytoplasmic processes
26
each osteon is based around....
a haversian canal (osteoclast erosion). the cannal carries vessels and nerves and connects to the marrow cavity
27
osteons are connected by
oblique volkmanns cannal
28
what is the appearance of red marrow and air space
haemopoietic
29
what is the appearance of yellow marrow and air space
adipose
30
what is pneumatised marrow
full of air e.g. vulture metacarpus
31
describe the osteoid matrix
1/3 organic type 1 collagen and 2/3 hydroxyapatite with adsorbed calcium carbonate
32
what is the bone composition
varies from rigit but btrille to more flexible
33
what did the bone evolve as (purpose)
phosphate store - unpredictable levels in the sea water e.g. decrease after algal blooms
34
what are osteoclasts
myeloid blood cell derived, multinucleate up to 0.15mm, short lived > 10 days.
35
what is bone formation/destruction controlled by
hormonally by parathyroid hormone, calcitonin and vitamin D
36
how can location classify bone
axial and appendicular, cranial and post cranial
37
how can morphology classify bone structure
long, short, flat, irregular, sesamoids
38
how can embryology classify bones
somatic = sclerotome and body wall. visceral. sesamoids.
39
how can tissue of formation classify bones
endochondral e.g. long bones or membrane e.g. skull flat bones
40
what are the long bones blood supply
periosteal aa, epiphyseal aa, metaphyseal aa
41
what is membrane bone?
evolutionary distinct from fish, devolpmentally distinct due to forming in condensed sheets of fibrous tissue. cancellous bone + marrow sandwiched between two layers of compact bone and periosteum
42
causes of fracture
external trauma (can occur anywhere) or internal mechanical overload trauma (specific)
43
which fractures are more important
cortical more important than cancellous except vertebral compressions and implant stability
44
which is stronger mineral or collagen
mineral is stronger in compression than collagen in extension
45
how does bone exhibit anistrophy
stronger in direction parallel to osteons