bone and cartilage Flashcards

1
Q

what is a eurypholus

A

bony fish

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2
Q

what is a hybodus

A

cartilaginous fish

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3
Q

what are the roles of periosteum

A

1 major role in bone formation 2 tendons, ligaments and joint capsules attach to it not directly to bone. 3 carries blood vessels and nerves 4 major role in bone repair post fracture

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4
Q

what is the epiphysis

A

found at the end of a long bone after the diaphysis

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5
Q

what is the diaphysis

A

shaft, cylindrical and narrow

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6
Q

where is the endosteum found

A

lining marrow cavity

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7
Q

what is the bone made up of

A

cancellous/spongy/trabeculae/with spicules

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8
Q

how is a fracture created

A

mineral shears at 45degrees in compression, collagen snaps transversely in tension, torsion creates a helical fracture, bending causes compression and tension on opposite sides

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9
Q

what is a mesenchyme cell

A

undifferentiated fetal connective tissue

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10
Q

what are chrondoblasts and osteoblasts

A

active cells that can lay down membrane cartillage

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11
Q

what are chrondocytes and osteocytes

A

resting in lacunae

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12
Q

what are the functions of bone 9

A

1 struts, 2 levers 3 protects 4 elastic potential energy store 5 acoustic 6 display 7 combat 8 blood cell prod 9 mineral store

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13
Q

describe the features of cartilage

A

firm extracellular chondrin matrix, sulfated mucopolysaccharide gel + network of type 2 (UNUSUAL) collagen fibres

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14
Q

what is cartilage described as

A

reinforced concrete - gel resists tension and fibres resist compression

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15
Q

what is cartilage laid down by

A

chrondoblasts

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16
Q

where are resting chrondrocytes

A

in 2-4 cell colonies in lacunae, no nerves, rarely blood vessels, often surrounded by perichondrium

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17
Q

types of cartilage

A

hyaline skeletal, elastic skeletal, fibrocartilage skeletal, articular and hyaline model precursor

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18
Q

what is hyaline skeletal

A

simplest, may mineralise, found in upper respiratory tract, ventral ribs

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19
Q

what is elastic skeletal

A

contains elastin fibres too as in the external ear, upper respiratory tract

20
Q

what fibrocartilage skeletal

A

alternating layers of hyaline cartilage and collage found in intervertebral discs, scuta, labra, menisci and discs

21
Q

what is articular cartillage

A

complex partly fibrous/ partly hyaline from

22
Q

what is hyaline model precursor

A

for bone development

23
Q

describe the structure of long bones

A

constantly remodelled, yielding many parallel cylinders called OSTEONS

24
Q

what is an osteon made up of

A

concentric cylinders of matrix interspersed with lacunae

25
Q

what does each lacunae contain

A

a resting osteocyte, they are stellate with radiating tiny canniculi permeating bone containing cytoplasmic processes

26
Q

each osteon is based around….

A

a haversian canal (osteoclast erosion). the cannal carries vessels and nerves and connects to the marrow cavity

27
Q

osteons are connected by

A

oblique volkmanns cannal

28
Q

what is the appearance of red marrow and air space

A

haemopoietic

29
Q

what is the appearance of yellow marrow and air space

A

adipose

30
Q

what is pneumatised marrow

A

full of air e.g. vulture metacarpus

31
Q

describe the osteoid matrix

A

1/3 organic type 1 collagen and 2/3 hydroxyapatite with adsorbed calcium carbonate

32
Q

what is the bone composition

A

varies from rigit but btrille to more flexible

33
Q

what did the bone evolve as (purpose)

A

phosphate store - unpredictable levels in the sea water e.g. decrease after algal blooms

34
Q

what are osteoclasts

A

myeloid blood cell derived, multinucleate up to 0.15mm, short lived > 10 days.

35
Q

what is bone formation/destruction controlled by

A

hormonally by parathyroid hormone, calcitonin and vitamin D

36
Q

how can location classify bone

A

axial and appendicular, cranial and post cranial

37
Q

how can morphology classify bone structure

A

long, short, flat, irregular, sesamoids

38
Q

how can embryology classify bones

A

somatic = sclerotome and body wall. visceral. sesamoids.

39
Q

how can tissue of formation classify bones

A

endochondral e.g. long bones or membrane e.g. skull flat bones

40
Q

what are the long bones blood supply

A

periosteal aa, epiphyseal aa, metaphyseal aa

41
Q

what is membrane bone?

A

evolutionary distinct from fish, devolpmentally distinct due to forming in condensed sheets of fibrous tissue. cancellous bone + marrow sandwiched between two layers of compact bone and periosteum

42
Q

causes of fracture

A

external trauma (can occur anywhere) or internal mechanical overload trauma (specific)

43
Q

which fractures are more important

A

cortical more important than cancellous except vertebral compressions and implant stability

44
Q

which is stronger mineral or collagen

A

mineral is stronger in compression than collagen in extension

45
Q

how does bone exhibit anistrophy

A

stronger in direction parallel to osteons