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Pharmacology > Blood Sugar Agents > Flashcards

Blood Sugar Agents Flashcards

1
Q

Onset of Regular Insulin

A

30-60 minutes

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2
Q

Peak of Regular Insulin

A

2-4h

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3
Q

Duration of Regular Insulin

A

6-12h

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4
Q

What insulins are 24 hours duration

A

NPH and Glargine

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5
Q

What insulins are fast acting

A

lispro <15min, glulisine 2-5min, aspart 10-20min, inhaled insulin 12-15min

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6
Q

Sulfonylureas have two generations which is safer

A

second generation

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7
Q

What drugs are sulfonylureas

A

Tolbutamide, Glipizide, Glyburide

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8
Q

What classes of drugs are used to regulate glucose in Type 2 diabetes

A

Sulfonylureas, Biguanides, DPP-4 inhibitors, Meglitinides, SGLT-2 Inhibitors, Thiazolidinediones, GLP-1 Agonists

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9
Q

What drug is a Biguanide

A

metformin

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10
Q

What is a very important contraindication for Metformin specifically?

A

BBW: Metabolic acidosis/lactic acidosis

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11
Q

What is a very important DDI/caution for Metformin?

A

Radiologic contrast, and Iodine containing contrast media, must wait 48 hours after metformin admin

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12
Q

T or F the first line in treatment for Type 2 DM is?

A

Metformin

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13
Q

What are the DPP-4 Inhibitors?

A

-gliptin
Sitagliptin

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14
Q

What are the contraindications for all type 2 diabetes medications

A

Type 1 Diabetes and DKA
Hypersensitivity

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15
Q

Meglitinides drugs?

A

-glinide
Repaglinide
Nateglinide

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16
Q

SGLT-2 Inhibitors

A

-gliflozin
Canagliflozin

17
Q

SGLT-2 inhibitors can be used in pregnancy?

A

No 2nd and third trimester might cause renal effects of fetus

18
Q

Thiazolidinediones

A

-glitazone
Pioglitazone

19
Q

What are the contras of Pioglitazone

A

severe heart failure = excacerbates the heart failure

20
Q

GLP-1 Agonists

A

Semaglutide
Exenatide

21
Q

Glucose

A

raises glucose level in blood for hypoglycemia

22
Q

What are the DDI for glucose admin

A

anticoagulants increase risk of bleeding

23
Q
A

Pharmacology (21 decks)

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