Anitseizure Flashcards
Status Epilepticus
a sx lasting over 5min with no period of rest
what meds are used to treat status epilepticus
phenobarbital
clonazepam
phenotonin
What meds are used for absent sz
succinimides
what is an absent sz
abrupt LOC for ~ 5 sec
3y/o>adolescent
no muscle contraction
Tonic clonic sz is
contraction of muscles followed by postictal period
myoclonic sz
generalized sz
T or F sz meds can affect the fetus
T risk v benefit
Hydantonins
Phenytoin
Action of Phenytoin
stabilize nerve membranes/decrease excitability
Contraindications of phenytoin
allergy
Caution of phenytoin
elderly/debilitated pt
renal/liver impair
depression/psychosis
ADE of phenytoin
CNS depressed
cardiac arrhythmias
hypoTN
SEVERE HEPATOTOXICITY
What is a common ADE for all sz meds
urinary retention
except GABA and Succinimides
What should not be taken with any antisz med
alcohol
What barituates are used for sz
phenobarbitol
primidone
ADE of benzos/barbituates
drowsy
decreased HR and BP
DYSPNEA/SLOWED BREATHING
BBW for Benzos/Barbituates
profound sedation > no breathing >coma >death
What benzos work for sz
clonazepam
diazepam
Succinimides
-suximides
ADE succinimides
CNS depress
Bone Marrow Suppress
SJS
What should not be given with Succinimides
Primidone, they make primidone not work
Gaba Modulators
valproic acidA
Action of valproic acid
decrease normal electricity of brain
Indication of GABA mods
myoclonic sz
Cautions of GABA
hepatic/renal impair
Contras of GABA
allergy
ADE of GABA
CNS depress
livertoxic
pancreatitis
What is a MAJOR GABA Mod ADE
DRESS
Drug
Rxn
w/ Eosinophilia
and Systemic
Symptoms
Carbamazepine
BBW = serious skin rxn
Lamotrigine
BBW: serious skin rxn
Levetriaetam
Keppra
BBW: serious skin rxn
can be given to pt w/ liver impairment
Topiramate
can cause serious skin rxns
Indications of Other sz drugs
sz
Abs contras for all sz meds
allergy
ADE for all sz meds
CNS depressents
