Blood pt 2 Flashcards

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1
Q

term for stoppage of bleeding

A

hemostasis

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2
Q

3 ways of hemostasis

A

vascular spasms, platelet plug, coagulation

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3
Q

explain what happens in vascular spasms

A

the smooth muscle of a blood vessel wall constricts to stop bleeding

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4
Q

explain what happens in platelet plug formation

A

involves the clumping of platelets around the damage to stop the bleeding

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5
Q

explain what happens in coagulation

A

formation of prothrombinase, conversion of prothrombin into thrombin, and conversion of soluble fibrinogen into insoluble fibrin

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6
Q

major blood groups

A

A, B, AB, O

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7
Q

2 antibodies that help determine blood groups

A

antibody A and antibody B

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8
Q

what vitamin is needed for normal clot formation

A

vitamin K

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9
Q

disorder d/t Rh incompatibility between mother and fetus

A

hemolytic disease of the newborn

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10
Q

how do extrinsic pathways and intrinsic pathways differ

A

extrinsic pathways occur more rapidly and involve clotting factor X. intrinsic pathways occurs more slowly and involves clotting factor XIII, clotting factor X, and clotting factor V

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11
Q

explain the conditions that may cause hemolyic disease of the newborn

A

a) At birth, a small quantity of fetal blood usually leaks across the placenta into the maternal bloodstream. A problem can arise when the mother is Rh- and the baby is Rh+, having inherited an allele for the Rh antigens from the father

b) on exposure to Rh antigen, the mother’s immune system responds by making anti-Rh antibodies

c) During a subsequent pregnancy, the maternal antibodies cross the placenta into the fetal blood. If the second fetus is Rh+, the ensuing antigen-antibody reaction causes agglutination and hemolysis of fetal RBCs. Result is HON

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