Blood Flashcards
Blood
Made up of plasme (55%) and formed elements (45%)
- complex transport medium that performs vital pickup and delivery services for the body
- keystone of body’s heat-regulating mechanism
Formed elements
Various kinds of blood cells: red blood cells, white blood cells, and platelets
Blood volume
- 8% of total body weight in average-sized adults
- blood volume varies according to age, body type, sex, and method of measurement
Females: 4-5 liters
Males: 5-6 liters
Composition of blood
- whole blood separates if allowed to stand or spun in a centrifuge
Hematocrit
The volume percent of red blood cells in whole blood
Erythrocytes
Red blood cells
- shaped like tiny, bicóncava discs
- hemoglobin, the red protein pigment, is the primary component
- red blood cells are the most numerous of the formed elements
Function of RBC
- play a critical role in the transport of oxygen and carbon dioxide in the body
- both of these functions depend on hemoglobin
- the total surface area of all the RBCs in an adult is enormous: equal to an area larger than a football field
Leukocytes
White blood cells
- 5 types (neutrophils, eosinophils, basophils, lymphocytes, monocytes)
- classified according to presence or absence of granules and the staining quality of their cytoplasm
Granulocytes
Include WBCs that have larde granules in their cytoplasm
- neutrophils - eosinophils - basophils
Agranulocytes
Include WBCs without cytoplasmic granules
- lymphocytes - monocytes
Neutrophils
- make up approx 65% of total WBC count in normal blood sample
- they are highly mobile and very active phagocytes cells
- they migrate out of blood vessels and enter the tissue space
- these cells are attracted to the site of an infection in repsonse to an inflammatory response
Eosinophils
- typically account for 2-5% of circulating WBC
- they are numerous in the mucous membranes of respiratory and digestive tracts
- weak phagocytes: capable of ingesting inflammatory chemicals and proteins associated with antigen-antibody reaction complexes
- mainly release granules that regulate body’s immune response
- provide protection against infections caused by parasitic worms and allergic reactions
Basophils
The least numerous of the WBC- only account for 0.5-1% of total WBC count
- granules contain histamine (inflammatory chemical)
Lymphocytes
- these are the smallest of the WBC
- they are the second most numerous type of WBC, next to neutrophils
- account for approx 25% of circulating WBC
- two types (T lymphocytes and B lymphocytes)
- both have important roles in immunity
Monocytes
The largest type of leukocyte
- mobile and highly phagocytes cells
- capable of engulfing large bacterial organisms and viral-infected cells