Blood Flashcards

1
Q

functions

A
  • transportation: oxygen, nutrients, wastes, co2, hormones, etc.
  • defense: against pathogens
  • regulatory: body temp, water-salt balance, body pH
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2
Q

albumins

A

plasma protein

  • for plasma osmotic pressure and transport
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3
Q

globulins

A

plasma protein

  • transport lipids + fat-soluble vitamins
  • some are antibodies
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4
Q

fibrinogen

A

blood clot formation

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5
Q

hematopoieisis

A

process of blood stem cell differentiation

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6
Q

rbc’s

A

lacks nucleus, few organelles, shape increases surface area, hemoglobin molecule (each one binds 4 O2)

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7
Q

rbc production cycle and negative feedback

A

red bone marrow -> increased oxygen delivery to tissues -> inhibits erythropoeitin (EPO) release -> decreased oxygen delivery to tissues -> kidney EPO released -> old cells destroyed by liver/spleen -> epo increase -> production

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8
Q

anemia

A

too few rbc’s/hemoglobin

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9
Q

sickle-cell anemia

A

genetic, rbc’s sickle-shape that tend to rupture

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10
Q

hemolytic disease of the newborn

A

incompatible blood types -> rupturing of blood cells in a baby before and after birth

  • Rh- mother + 2nd(+) Rh+ baby
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11
Q

wbc

A

red bone marrow, nucleus, production regulated by colony-stimulating factor (CSF), also found in tissues, immune system, etc.

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12
Q

eosinophil

A

granular wbc stained by eosin (red)

  • small %
  • large granules function in parasitic worm infections
  • allergies
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13
Q

basophil

A

granular wbc stained by basic dyes (blue)

  • small %
  • histamine (attracts other wbcs, dilates blood vessels)
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14
Q

neutrophil

A

granular wbc unstained

  • 50-70%
  • phagocytosis
  • component of pus
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15
Q

lymphocyte (B/T-cells)

A
  • agranular
  • 25-35%
  • develops B and T cells for immune cystemd
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16
Q

monocyte

A
  • in tissues

- macrophages use phagocytosis

17
Q

severe combined immunodeficiency disease (SCID)

A

inherited

- wbc’s lack enzyme to fight any infection

18
Q

leukemia

A

groups of cancers affect wbc’s

19
Q

infectious mononueclosis

A

“kissing disease”

  • epstein-barr virus (EBV) infects lymphocytes
  • fatigue, sore throat, swollen lymph nodes
20
Q

platelets

A
  • megakaryocyte fragments

- blood proteins thrombin + fibrinogen for blood clotting

21
Q

blood clot process step 1

A

injured cells in vessel walls and platelets release clotting factors

22
Q

blood clot process step 2

A

clotting factors convert inactive blood protein to prothrombin activator

23
Q

blood clot process step 3

A

prothrombin activator: prothrombin -> thrombin (liver)

24
Q

blood clot process step 4

A

thrombin: fibrinogen -> fibrin (liver)

25
blood clot process step 5
fibrin network traps rbcs and platelets, forming blood clot
26
thrombocytopenia
platelets # low
27
thromboembolism
when a clot forms (thrombus) and breaks off from its origin site (embolus) and plugs another vessel
28
hemophilia
genetic disorder | - unable to properly clot internally and externally
29
antigen
foreign substance (eg polysaccharide, protein) that stimulates immune response
30
antibody
proteins made in response to antigen (binds to it to eliminate) - very specific, numerous variety
31
type A
- A antigen - Anti-B - Receives A, O
32
type B
- B antigen - Anti-A - Receives B, O
33
type AB
- AB antigen - none - receives all
34
type O
- no antigen - Anti-A/B - receives O
35
Rh factor
Rh antibodies develop when exposed to Rh factor from another (fetus)
36
hemolytic disease of the newborn prevention
- Rh- women given injection of anti-RH antibodies