Biology Integumentary and Immune Systems Flashcards
The ___ serves as the initial barrier to infection and prevents a large proportion of environmental microorganisms from entering the body
integument
The ___ provides a physical barrier to prevent the entrance of pathogens into the body
integument
Many ___ live on the surface of skin and make up the normal skin flora, also known as the skin microbiome
microorganisms
The skin is divided into two layers, the dermis and the ___, which are connected together by the basement membrane
epidermis
The dermis contains the blood supply to the skin and most of the specialized cells, whereas the epidermis contains mainly ___, which differentiate into corneocytes: protective, waterproof cells that do not undergo further replication and are routinely sloughed off and replaced
keratinocytes
Hair serves to direct sweat and waste away from the skin, helping with evaporative cooling when the ___ is hot
body
Mucous secretions in the nose and ___ secretions in the eyes help prevent foreign organisms from entering the body and resist infection
aqueous
The immune system has two major types of ___: innate and adaptive
immunity
Innate immunity is comprised of the body’s ___, generalized defenses against pathogens
initial
During inflammation, injured cells release ___, such as histamine, that dilate and increase the permeability of blood vessels
chemicals
Granulocytes are attracted to the site of injury, where thy ___ antigens and antigenic material
phagocytize
___, the most common type of granulocyte, are often the first responders to sites of inflammation
neutrophils
Neutrophil counts are often elevated during the acute stages of ___ and are the main component of pus
inflammation
Eosinophils are much less common and are responsible for ___ responses
immune
basophils and related ___ cells are similarly involved in allergic responses and parasite infections, and often are responsible for the release of histamine, which stimulates blood vessel dilation as previously described
mast
Monocytes are large, long-lived immune cells that can differentiate into macrophages and ___ cells
dendritic
Antigen-presenting cells present ___ for recognition to mediate a cellular immune response
antigens
The main role of ___ is to phagocytize dead cells and pathogens
macrophages
Dendritic cells are found in areas of the body where contact with the external environment is more ___
common
There are two types of ___ immunity: cell-mediated, which is mediated by T lymphocytes, and humoral, which involves antibody production by B lymphocytes
adaptive
___, or T cells, are an important component in cell-mediated immunity
T lymphocytes
Travel from the bone marrow to the thymus via the ___
bloodstream