Biology Genetics Flashcards
Mendel’s First Law: Law of Segregation posits that genes exist in alternative forms (now referred as alleles). A gene controls a specific trait in an organism.
An organism has two alleles for each inherited trait, one inherited from each parent.
The two alleles segregate during meiosis, resulting in gametes that carry only one allele for any given inherited trait.
If two alleles in an individual organism are different, only one will be fully expressed, and the other will be silent. A dominant allele only requires one copy present to be expressed whereas a recessive allele must have two copies present to be expressed. In genetics problems, dominant alleles are typically capital letters, and recessive alleles are assigned lowercase letters. organisms that contain two copies of the same allele are ___ for that trait; organisms that carry two different alleles are heterozygous. The dominant allele is expressed in the phenotype. This is known as Mendel’s Law of Dominance.
homozygous
Because only one trait is being studied in this particular mating, it is referred to as a ___ cross
monohybrid
The individuals being crossed are the parental or P generation; the progeny generations are the ___ or F generations, with each generation numbered sequentially
fillial
A ___ square indicates all the potential progeny genotypes, and the relative frequencies of the different genotypes and phenotypes can be easily calculated
punnet
Mendel also developed the testcross, a diagnostic tool used to determine the ___ of an organism
genotype
Homozygous ___ organisms always breed true
recessive
Generally, the closer the genes are on the chromosome, the more likely they are to be ___ together
inherited
Dihybrid cross involves the analysis of two ___ of inheritance
traits
An allele is incompletely dominant if the phenotype of the heterozygote is an ___ of the phenotypes of the homozygotes
intermediate
Codominance occurs when ___ alleles exist for a given gene and more than one of them is dominant
multiple
Only two alleles are present in any single individual (ABO blood groups) but the population contains ___ three alleles
all
In codominance, however, both alleles in the genotype are expressed at the same time without a ___ of phenotype
blending
In sexually differentiated species, most chromosomes exist as pairs of ___ called autosomes, but sex is determined by a pair of sex hormones
homologues
All humans have 22 ___ of autosomes; additionally, women have a pair of homologous X chromosomes, and men have a pair of heterologous chromosomes, an X and a Y chromosome
pairs
Genes located on the X or Y ___ are called sex-linked
chromosome
Examples of sex-linked recessives in humans are the genes for ___ and color-blindness
hemophilia
Sex-linked ___ generally affect only men; they cannot be passed from father to son, but they can be passed from grandfather to grandson via a daughter who is a carrier, thereby skipping a generation
recessives
Mutations are changes in the genetic information ___ in the DNA of a cell
coded
Mutagenic ___ induce mutations
agents
Mutagenic agents are ___ also carcinogenic (cancer-causing)
sometimes
In a point mutation, a nucleic acid is replaced by another ___ acid
nucleic
As a result of a point mutation, the new codon may code for the same amino acid (___ mutation), the new codon may code for a different amino acid (missense mutation), the new codon may be a stop codon (nonsense mutation)
silent
While point mutations may lead to proteins of a different length than the native protein, they do not affect the length of the genome itself as seen with ___ mutations
frameshift
In a frameshift mutation, ___ acids are deleted or inserted into the genome sequence
nucleic