B8-018 Diseases/Disorders of Gestation Flashcards
2 screening options for gestational diabetes
Two step approach: 1 hr glucose challenge test
One-step approach: 2 hr glucose tolerance test
what medication is the “gold standard” for controlling hyperglycemia in pregancy?
insulin
(metformin is a safe oral alternative)
advanced maternal age is considered any mother who will be […] or older at time of delivery
35
risk factors associated with AMA [4]
aneuploidy
early onset gestational diabetes
preterm delivery
stillbirth
preeclampia is new onset HTN on two separate occasions […] hours apart after […] weeks gestational age plus proteinuria
4 hours
20 weeks
new onset HTN with either proteinuria or end-organ dysfunction after 20 weeks gestation
preeclampsia
only intervention shown to decrease the risk of preeclampsia in subsequent pregnancies
aspirin
(decreases thromboxane: prostacyclin)
risk factors for the development of preeclampsia
hx of preeclampsia
multifetal gestation
chronic HTN
diabetes
kidney disease
autoimmune diseases
AMA
obesity
aspirin should be given to women at a high risk of developing preeclampsia beginning at […] weeks gestation
12
BP > 140/90 after 20 weeks gestation
no preexisting hypertension
no proteinuria or end-organ damage
gestational hypertension
hypertension prior to 20 weeks gestation suggests
chronic (overt) hypertension
antihypertensives safe in pregnancy [4]
hydralazine
a-methyldopa
labetalol
nifedipinie
(Hypertensive Moms Love Nifedipine)
caused by abnormal placement of the placental spiral arteries causing endothelial dysfunction, vasoconstriction, and ischemia
preeclampsia
prophylaxis for preeclampsia
aspirin
treatment for preeclampsia
antihypertensives
IV magnesium sulfate
delivery
preeclampsia with seizures
eclampsia
preeclampsia with thrombotic microangiopathy of the liver
HELLP syndrome