B30 Flashcards
1
Q
antineoplastic drugs
A
Carboplatin Cysplatin Cyclophosphamide Doxorubicin Vincristine Masitinib
2
Q
4 characteristics of cancer cells
A
uncontrolled proliferation
loss of function
invasive
ability to metastatise
3
Q
goal of anticancer drugs
A
to extend quality of life
4
Q
side effects of anticancer drugs
A
individual sensitivity narrow ti time dependant occurrenct nausea, vomitting diarrhoea myelopsuppression sterile cystitis
5
Q
types of anticancer drugs
A
antimetabolites agents that directly modify dna structure topoisomerase inhbitors microtubules gss
6
Q
resistance to anticancer
A
decrease amount of drug taken by cell increase inactivation increase conc of target enzymes increase utilisation of alternative metabolic pathways rapid repair of drug altered activity of enzyme mutations in genes
