B13

Question 1

pharmacological effects of central muscle relaxants

Answer 1

decrease motor activity

paralysis of voluntary muscles

no loss of conscioussness

Question 2

use of central muscle relaxants

Answer 2

potentiate effect of anaesthetics

to control certain spasmodic and painful disorders

Question 3

drugs to know muscle relaxants

Answer 3

guaiphenisin
atracurium
pancuronium

Question 4

2 classes of peripheral muscle relaxants

Answer 4

depolarising

competitive

Question 5

use of neuromuscular blocking agent

Answer 5

adjuvant in surgery
TIVA
assist intubation
corneal/retinal surgeries
therapy of spastic disorders

Question 6

depolarising

Answer 6

succinylcholine (chloride)

Question 7

phase I block

Answer 7

depolarising of the motor end plate. not reversed by cholinesterase inhibitors

Question 8

phase II block

Answer 8

side effect after repolarisation, membrane cant easily be depolarised again

Question 9

non depolarising/competitive

Answer 9

antagonize NAch receptors

prevent muscle cell depolarisation

complete block leading to flaccid and motor paralysis

Question 10

atracurium

Answer 10

intermediate duration of action

safe in liver and kidney

Question 11

pancuronium

Answer 11

long acting