B1

Question 1

2 different types of mechanisms of actions

Answer 1

physical interactions

biochemical interactions

Question 2

physical intereactions

Answer 2

osmotic diuretics e.g. mannitol
antacids e.g. MgOH
laxatives e.g. MgSo
chelates e.g. EDTA

Question 3

2 different types of biochemical interactions

Answer 3

non receptorial

regeptorial-ligands

Question 4

examples of non receptorial drug activity

Answer 4

inhibition of enzymes
dna damage
transporters
ion channels

Question 5

examples of receptorial-ligands

Answer 5

ligand gates ion channels
g protein coupled receptors
receptor activated tyrosine kinases
intracellular nuclear receptors

Question 6

inotropic effect

Answer 6

effect on the force of the muscle contraction

Question 7

chronotropic effect

Answer 7

effect on heart rate

Question 8

dromotropic effect

Answer 8

effect on conduction speed of the av node

Question 9

Gs

Answer 9

B1

B2

Question 10

Gi

Answer 10

M2

Alpha2

Question 11

Gq

Answer 11

histamine
alpha 1
serotonin

Question 12

B1

Answer 12

stimulating
+ve chronotrpoic
+ve inotropic

Question 13

B2

Answer 13

inhibitor
bronchodilation
vasodilation

Question 14

M2

Answer 14

cholinergic receptors

Question 15

alpha 2

Answer 15

sedation

anaesthesia

Question 16

histamine

Answer 16

vasoconstriction

Question 17

alpha 1

Answer 17

smooth muscle relaxation

vasoconstriciton

Question 18

serotonin

Answer 18

thermoregulation

Question 19

intracellular nuclear recpetors

Answer 19

steroids