ASD

Question 1

4 Core Symptoms

Answer 1

Impairment in social interaction and social communication
Restrictive repetitive and stereotype patterns of behavior, interest, or activities
Present in early developmental period
Some specific impairment, whether social, activities, or whatever

Question 2

Asperger’s Disorder

Answer 2

Removed from DSM V, instead ASD w/ no language impairment

Question 3

2 Gross Features of ASD Brains

Answer 3

Larger frontal lobe and smaller corpus callosum

Question 4

5 Neuropathological Features

Answer 4

Increased neuronal density in hippocampus/amygdala/limbic system
Decreased Purkinje cell #
Abnormal cell migration

Question 5

3 Paths to ASD

Answer 5

Abnormal cell migration
Excitatory-inhibitory imbalance
Abnormal synapse formation and dendritic spines (increased # and thinner/longer)

Question 6

Rett’s Disorder

Answer 6

Normal development for awhile, then sometime in early years goes awry and develop ASD-like symptoms. Due to XL mut, so males die so really only females present