Approach to back pain Flashcards

1
Q

Learning Outcome:

A
  1. Mechanical
    - PID
    - spondylosis
    - spondylolisthesis
    - spinal stenosis
    - scoliosis
    - kyphosis
    - trauma
  2. Infection
    - pyogenic osteomyelitis
    - discitis
    - tuberculosis
    - epidural abscess
  3. Inflammatory
    - ankylosing spondylitis
    - reiter’s syndrome
    - psoriatic arthritis
  4. tumors
    - extradural: metastasis
    - intradural: meningioma, lipoma, neurofibroma
    - intramedullary: ependymoma, astrocytoma
  5. vascular
    - haematoma
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2
Q

Pattern of neurological deficits

A
  1. Myelopathy
    i. UMNL
    - loss of motor level of injury and below
    - hyperreflexia (babinski, BCR intact, inverted brachioradialis reflex, hoffman’s sign, jaw jerk)
    - hypertonia (anal tone intact)
    ii. somatosensory
    - anterolateral: pain, temp, crude touch
    - dorsal column: vibration, proprioception, fine touch
    iii. autonomic
    - bladder
    - bowel
    * weakness, paraesthesia, numbness
    * pain less common than radiculopathy
    * autonomic common
  2. Radiculopathy
    i. LMNL
    - loss of motor usually at affected levels only (1-2 segments)
    - hyporeflexia
    - hypotonia
    ii. Somatosensory
    - anterolateral: pain, temp, crude touch
    - dorsal column: vibration, proprioception, fine touch
    iii. Autonomic
    - rarely involve unless sacral nerve roots involved
    *pain is more common than myelopathy, shooting
    due to dura irritation
    *weakness, tingling, paraesthesia
    *autonomic rare
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3
Q

Prolapse Intervertebral Disc pathology

A
  1. epids: 20-45 yo
  2. stages:
    i. protrusion: bulging while annulus intact
    ii. rupture: annulus rupture
    iii. extrusion: bulges to either side of pll
    iv. sequestration: part of nucleus in spinal canal or intervertebral foramen
  3. compression area:
    i. posterolateral: nerve root compression proximal to point of exit, upper (most common)
    ii. central: cauda equina
    iii. foraminal: involve existing nerve, lower
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4
Q

Prolapse Intervertebral Disc diagnosis

A

Hx

  • back pain (tearing of annulus fibrosis or pll)
  • sciatica pain (disc irritates the dura of adjacent nerve roots)
  • increase with stooping forward of lifting (compress disc)
  • worse by coughing or straining
  • associated with: weakness, numbness, paraesthesia
  • if cauda: perineal numbness, urinary retention

Pe:

  • listing to one side (avoid nerve root compression) depends bulge medial or lateral to nerve root
  • knee slightly flex (relax tension on sciatic nerve)
  • restricted back movement
  • listing increase wih forward flexion
  • tenderness in midline lower back, paravertebral spasm
  • SLR: +ve
  • bowstring test: +ve
  • crossed sciatic tension: may be +ve
  • femoral stretch test: +ve
  • neurological: weakness, wasting, diminished reflex, dermatomal sensory loss
  • L5: Knee flexion, big toe extension
  • S1: Plantar flexion, eversion, depress ankle jerk, sensory loss lateral border of foot
  • at most 2 levels are affected

X-ray:

  • tro exclude bone disease
  • osteophytes due to space narrowing
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5
Q

Prolapse Intervertebral Disc management

A
  1. Rest: hips and knees slightly flex
  2. Reduction: best rest, traction for 2 weeks
  3. Removal:
    i. indication
    - persistent pain after conservative tx (failed 6 weeks)
    - cauda equina
    - neurological deterioration
    ii. how
    - laminotomy
    - discectomy
  4. Rehabilitation
    - isometric exercise: how to sit, lie, bed and lift with least strain
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6
Q

Spondylolisthesis pathology

A
  1. definition: forward translation of one segment of spine upon another
  2. epidemiology: 20 years old
  3. classification:
    i. dysplastic (20%): defects in superior sacral facet. associated with spina bifida
    ii. lytic/isthmic (50%): defects in pars interarticularis due to repetetive breaking and healing (spondylosis) (young)
    iii. degenerative (25%): defects in disc or facet joints L4/L5 middle aged women, associated with osteoarthritis, crystal arthropathy (>50 yo)
    iv. post traumatic
    v. pathological (TB, Neoplasm)
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7
Q

Spondylolisthesis diagnosis

A

Hx

  • backpain
  • intermittent
  • onset after exercise or strain
  • +/- sciatica

Pe

  • flat buttocks
  • transverse loin crease
  • lumbar spine in front of sacrum
  • step deformity
  • hamstring tightness

X-ray

  • lateral: forward shifting of vertebrae
  • oblique: break in pars interarticularis
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8
Q

Spinal Stenosis pathology

A
  1. definition: abnormal narrowing of the central canal, the lateral recesses or the intervertebral foramina to the point where the neural elements are compromised
  2. classification
    i. central stenosis: spinal canal, cause myelopathy
    ii. lateral stenosis: lateral recess or intervertebral foramen, cause radiculopathy
  3. causes:
    i. primary/congenital
    - congenital vertebral dysplasia (fail segmentation, incomplete closure or arch)
    - premature ossification of vertebral arch
    - Paget’s disease (bone thickening)
    ii. secondary/acquired
    - spondylosis
    - spondylolisthesis
    - pid
    - ossification of lig. flavum
    - post-operative fibrosis
    - tumors
    - fractures
  4. Narrowing area:
    i. central canal: thecal sac, lig. flavum, facet joint
    ii. lateral recess: superior facet, disc
    iii. foraminal: facet enlargement, overriding, disc
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9
Q

Spinal Stenosis diagnosis

A

Hx

  • elderly >50
  • pain, heaviness, numbness, paraesthesia of thighs, legs
  • after standing upright (reduce interlaminar space) or walking 10-15mins (Mechanical comprrssion of nerve root -> venous congestion, diminisehd arterial flow -> decrease impulse conduction)
  • relieved with bending forward (walking uphill)(increase by 12% in flexion), aggravated with extension (downhill) (decrease by 20% in extension)

X-ray

  • midsagittal diameter (AP) <11mm
  • interpedicular diameter (transverse) <16mm
  • degenerative features

MRI
- Narrowing of spinal canal <10mm

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11
Q

Acute Pyogenic Osteomyelitis diagnosis

A

Hx

  • RF: immunodeficient, elderly, distant foci infection, spine procedures
  • localised pain, intense, continuous
  • associated with spasm, restricted movement due to pain
  • sepsis: pyrexia

Pe

  • inflammation sign
  • pyrexia, tachycardia

Blood ix

  • TWBC raised
  • CRP, ESR raised
  • anti-staphylococcal antibody titre (ASOT)
  • blood culture

X-Ray

  • loss of disc height
  • irregularity of disc space
  • erosion of vertebral end plate
  • soft tissue swelling

MRI
- sensitive but not specific

Needle biopsy
- often organism not found

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12
Q

Acute Pyogenic Osteomyelitis management

A
  1. Bed rest
  2. Analgesic
  3. IV antibiotics 4-6 weeks
  4. Monitor TWBC, CRP, ESR decline
  5. Nutritional support, control comorbidity
  6. At discharge:
    - oral antibiotics 6-8 weeks
    - spinal brace
    - TCA, X-Ray: spontaneous fusion of infected vertebrae

++Operative tx

i. poor response to conversavative tx
ii. presence of neurological signs
iii. soft tissue abscess

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13
Q

Discitis

A
  1. Epidemiology: rare
  2. Source: Iatrogenic:
    - discography
    - chemonucleolysis
    - discectomy
  3. Diagnosis:
    - Hx of disc procedure
    - Back pain, muscle spasm
    - ESR elevation
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14
Q

Spinal Tuberculosis pathology

A
  1. Epidemiology: most common site of skeletal TB
  2. Pathology:
    i. start at vertebral body adjacent to disc (destruction, caseation): most commonly thoracic vertebrae
    ii. discitis
    iii. vertebral bodies collapse into each other, forming sharp angulation, progressive kyphosis (gibbus/khypos)
    iv. vertebrae recalcify, bony fusion
    ++ paravertebral abscess
    ++ cord damage die to: pressure by abscess, bone sequestra, ischaemia from spinal art. thrombosis
  3. Cx: Pott’s Paraplegia
    i. early onset paresis:
    - within 2 years
    - stage of inflammation, cold abscess, caseation, sequestration
    - good neurological recovery
    ii. late-onset parasis:
    - direct cord compression from increasing deformity, vascular cord insufficiency
    - poor neurological recovery
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15
Q

Spinal Tuberculosis diagnosis

A

Hx

  • intermittent flares of backpain
  • tb contact, diagnosed with tb
  • cold abscess
  • restricted spinal movement
  • neurological: paraesthesia, leg weakness, incontinence
  • night sweats, loa, low

Pe

  • kyphosis
  • spastic paraparesis

Ix

  • mantoux test
  • raised ESR
  • raised lymphocyte

X-Ray

  • narrowing of disc space
  • bone destruction, collapse, fusion
  • parasoinal soft tissue shadows (edema, abscess, swelling)

Needle biopsy
Spinal fluid analysis

MRI, CT
- involvement of cord compression, posterior vertebrae elements, paravertebral abscess, epidural abscess

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16
Q

Spinal Tuberculosis management

A

Principles:

  1. Eradicate or arrest disease
  2. Prevent or correct deformity
  3. Prevent paraplegia

Pharmacological:

  • 2 months aggressive: IR
  • 10 months maintenance: IRPE

Surgery:

  • indication:
    i. neurological involvement not responding to pharma tx
    ii. abscess
    iii. threatened or severe kyphosis
  • how: debridement and decompression (anterior spinal fusion with strut graft)
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17
Q

Acute Pyogenic Osteomyelitis pathology

A
  1. Epidemiology: uncommon. Occur among elderly, chronic disease, immunodeficient patient
  2. Etiology:
    i. Staph aureus (most common, 60%)
    ii. Gram -ve E.coli, Pseudomonas (immunodeficient)
  3. Sources:
    - haematogenous
    - iatrogenic (surgery, injection)
  4. Pathology:
    - vertebral end plate -> disc/ALL -> adjacent vertebrae
    - paravertebral soft tissue, psoas, buttocks
    - rarely involve spinal canal
18
Q

Ankylosing Spondylitis pathology

A
  1. Epidemiology
    - males more than female
    - teen to young adult (15-25 yo)
    - caucasian
  2. Definition: generalised chronic inflammatory disease affecting mainly spine and sacroiliac joint
    - less commonly shoulder, hip
    - rarely peripheral joints
  3. Pathology
    i. synovitis of diarthrodial joints
    - sacroiliac joint
    - vertebral facets
    - costovertebral
    ii. inflammation of fibro-osseus junction of syndesmotic joints and tendon -> granulation tissue -> fibrous tissue -> ossification and ankylosis
    - intervertebral discs
    - sacroiliac ligaments
    - symphysis pubis
    - manubrium-sterni
    iii. Extraarticular
    - low, fatigue
    - acute anterior uveitis
    - carditis
    - pulmonary fibrosis
  4. Complication
    - spinal fracture (c5-c7)
    - hyperkyphosis
    - spinal cord compression
    - lumbosacral nerve root compression
19
Q

Ankylosing Spondylitis diagnosis

A

Hx

i. Backpain
- intermittent
- worse in early morning, after inactivity
ii. stiffness
iii. fatigue, pain, swelling of joints
iv. achilles, intercoastal tenderness

Pe

  • marked stiffness of spine
  • stand upright with knee flexed
  • bend forward at hip (flattening of lower back)
  • diffuse tenderness over spine and sacroiliac joint
  • loss of lumbar lordosis, increased thoracic kyphosis, forward neck thrust
  • diminished spine movement in all direction (loss of extension earliest)
  • wall test +ve
  • restricted line of vision to few paces
  • reduce chest expansion

Blood
- ESR, CRP (high during active phase)

X-Ray

  • squaring of lumbar vertebrae (loss of anterior concavity)
  • syndesmophytes (ossification of ligament around disc) “bamboo spine!
  • erosion of sacroiliac joint
  • periarticular sclerosis
  • bone ankylosis
20
Q

Psoriatic arthritis diagnosis

A

Clinical features

  1. Joint pain
    - DIPJ, PIPJ, MCPJ
    - asymmetrical
  2. Skin
    - silvery plaque
    - extensor surfaces
  3. Hands
    - nail pitting
    - sausage digits (dactylitis)
  4. Chronic uveitis
  5. Enthesis
    - achilles
    - plantar fasciits
    - posterior tibialis
  6. Sacroilitis, spondylitis (1/3 of patient)