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Specialized Pharmacology MN650 > Antiprotozoal Drugs > Flashcards

Antiprotozoal Drugs Flashcards

1
Q

Chloroquine is used to treat?

A
  • amebiasis

- malaria

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2
Q

dehydroemetine is used to treat?

A

amebiasis

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3
Q

Iodoquinol is used to treat?

A

amebiasis

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4
Q

Metronidazole is used to treat?

A
  • amebiasis
  • giardiasis
  • trichomonas vaginalis
  • anaerobic cocci
  • anaerobic gram neg bacilli
  • anaerobic gram pos bacilli (C. Diff)
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5
Q

Paromomycin is used to treat?

A

amebiasis

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6
Q

Tinidazole is used to treat?

A
  • amebiasis
  • amebic liver abscess
  • giardiasis
  • trichomoniasis
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7
Q

Coartem is used to treat?

A

malaria

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8
Q

Malarone is used to treat?

A

malaria

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9
Q

Mefloquine is used to treat?

A

malaria

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10
Q

Primaquine is used to treat?

A

malaria

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11
Q

Pyrimethamine is used to treat?

A
  • malaria

- toxoplasmosis

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12
Q

Quinine/quinidine is used to treat?

A

malaria

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13
Q

What is amebiasis?

A

infection of the intestinal tract caused by Entamoeba hystolytica

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14
Q

What is the causative pathogen of amebiasis?

A

entamoeba hystolytica

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15
Q

How does entamoeba hystolytica enter the body?

A

fecal to oral route, ingestion of contaminated foods

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16
Q

What class of drug are cholorquine and dehydroemetine?

A
  • systemic amebicides

- intestinal wall and liver

17
Q

What class of drug are iodoquinol and paromomycin?

A
  • luminal amebicides

- work within the intestinal lumen

18
Q

What class of drug are metronidazole and tinidazole?

A
  • mixed amebicide

- work within the intestinal lumen, intestinal wall and liver

19
Q

Drugs to treat Amebiasis - Asymptomatic cyst carriers

+ fecal test

A

Iodoquinol or Paromomycin

20
Q

Drugs to treat Amebiasis -

  • Diarrhea/dysentery
  • Extraintestinal
A

Metronidazole plus (Iodoquinol or Paromomycin)

21
Q

Drugs to treat Amebiasis -Amebic Liver Abscess

A

Metronidazole or tinidazole plus (iodoquinol or paromomycin)

Specialized Pharmacology MN650 (28 decks)

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