Antiprotozoal Drugs Flashcards
Chloroquine is used to treat?
- amebiasis
- malaria
dehydroemetine is used to treat?
amebiasis
Iodoquinol is used to treat?
amebiasis
Metronidazole is used to treat?
- amebiasis
- giardiasis
- trichomonas vaginalis
- anaerobic cocci
- anaerobic gram neg bacilli
- anaerobic gram pos bacilli (C. Diff)
Paromomycin is used to treat?
amebiasis
Tinidazole is used to treat?
- amebiasis
- amebic liver abscess
- giardiasis
- trichomoniasis
Coartem is used to treat?
malaria
Malarone is used to treat?
malaria
Mefloquine is used to treat?
malaria
Primaquine is used to treat?
malaria
Pyrimethamine is used to treat?
- malaria
- toxoplasmosis
Quinine/quinidine is used to treat?
malaria
What is amebiasis?
infection of the intestinal tract caused by Entamoeba hystolytica
What is the causative pathogen of amebiasis?
entamoeba hystolytica
How does entamoeba hystolytica enter the body?
fecal to oral route, ingestion of contaminated foods
What class of drug are cholorquine and dehydroemetine?
- systemic amebicides
- intestinal wall and liver
What class of drug are iodoquinol and paromomycin?
- luminal amebicides
- work within the intestinal lumen
What class of drug are metronidazole and tinidazole?
- mixed amebicide
- work within the intestinal lumen, intestinal wall and liver
Drugs to treat Amebiasis - Asymptomatic cyst carriers
+ fecal test
Iodoquinol or Paromomycin
Drugs to treat Amebiasis -
- Diarrhea/dysentery
- Extraintestinal
Metronidazole plus (Iodoquinol or Paromomycin)
Drugs to treat Amebiasis -Amebic Liver Abscess
Metronidazole or tinidazole plus (iodoquinol or paromomycin)
