Alzheimer Drugs

Question 1

What is the biggest risk factor for Alzheimers?

Answer 1

aging

Question 2

What are the 3 cholinesterase inhibitors used to treat Alzheimers disease?

Answer 2

• Donepezil
• Rivastigimine
• Galantamine

Question 3

What type of drug is used to treat mild Alzheimer symptoms?

Answer 3

Cholinesterase inhibitors

Question 4

What type of drug is used to treat moderate to severe Alzheimer symptoms?

Answer 4

Cholinesterase inhibitors and consider memantine

Question 5

Cholinergic or parasympathetic effects?

Answer 5

• pupil constriction
• stimulates saliva
• slows HR
• bronchoconstriction
• bile release from liver
• stimulates peristalsis
• contracts bladder

Question 6

Memantine is what type of drug?

Answer 6

NMDA receptor antagonist

Question 7

Memantine is used to treat?

Answer 7

moderate to severe AD

Question 8

Memantine MOA?

Answer 8

• binds to NMDA receptor, blocking glutamate binding and opening of intracellular Calcium channels
• inhibits Calcium entry into cells

Question 9

Donepezil is used to treat?

Answer 9

mild, moderate or severe alzheimers

Question 10

Donepezil is what type of drug?

Answer 10

cholinesterase inhibitor

Question 11

Rivastigmine is use to treat?

Answer 11

alzheimers and dementia in PD

Question 12

Rivastigmine is what type of drug?

Answer 12

cholinesterase inhibitor

Question 13

Galantamine is use to treat?

Answer 13

mild to moderate alzheimers

Question 14

Galantamine is what type of drug?

Answer 14

cholinesterase inhibitor