Antimicrobials

Question 1

What are 2 antimicrobials (standalone and combo)?

Answer 1

bismuth

amoxicillin/tetracycline combo

Question 2

What is the role of bismuth in treating peptic ulcer disease?

Answer 2

Bismuth increases mucus secretion, disrupts bacterial cell wall adhesion to gastric mucosa, and reduces bacterial damage

Used specifically for treating gastritis caused by H. pylori infection.

Question 3

What is a common side effect of bismuth?

Answer 3

Black stool

This side effect is often harmless but can be alarming.

Question 4

What is the function of the amoxicillin/tetracycline combo?

Answer 4

Antibiotics inhibit bacterial cell growth and eliminate infection by Helicobacter pylori

Commonly used in the treatment of peptic ulcer disease and gastritis.

Question 5

What is a risk associated with using monotherapy for H. pylori infection?

Answer 5

Increases risk for resistance and ineffectiveness

It is recommended to use a combination of 2 antibiotics along with a proton pump inhibitor.

Question 6

What precaution should be taken regarding tetracycline use during pregnancy?

Answer 6

Pregnant people shouldn’t use it due to its effects on developing teeth

Tetracycline can cause permanent discoloration of teeth in children.

Question 7

Fill in the blank: H. pylori commonly infects the _______ areas.

Answer 7

glandular

This refers to glandular areas in the stomach where the bacteria reside.

Question 8

What is the indication for bismuth or amoxicillin/tetracycline combo?

Answer 8

Treatment of peptic ulcer disease and gastritis caused by a H. pylori infection.