Antimicrobials

Question 1

Which antibiotics inhibit cell wall synthesis?

Answer 1

Beta-lactams
- penicillins
- cephalosporins (1st, 2nd, 3rd gen)
- carbepenems

Glycopeptides (Vancomycin, Teicoplanin)

Question 2

Name glycopeptide abx

Answer 2

Vancomycin, Teicoplanin

topical bacitracin

Question 3

Vancomycin, Teicoplanin - aby type?

Answer 3

glycopeptide

Question 4

ceftriaxone - what kind of antibiotic is it?

Answer 4

3rd generation cephalosporin

inhibits cell wall synthesis

Question 5

How do β-lactams work?

Answer 5

Inactivate the enzymes that are involved in the terminal stages of cell wall synthesis (transpeptidases also known as penicillin binding proteins) – β-lactam is a structural analogue of the enzyme substrate
Bactericidal
Active against rapidly-dividing bacteria

Weakened cell wall results osmotic lysis of the bacterial cell

Question 6

How do you call the rash that you get when you treat EBV infection with penicillin?

Answer 6

infectious mononucleosis exanthema