Antimicrobial resitance Flashcards
What is a public health campaign that you have seen recently?
- Antimicrobial resistance.
- Specifically antibacterial resistance.
- TV broadcasts and posters in GP practices.
- Overuse and unnecessary use in humans and other animals (particularly farming) has led to increasing resistance.
- Traditional antibiotics such as penicillin are becoming increasingly obsolete as resistant strains such as MRSA develop.
- Use of newer, stronger antibiotics results in the same endpoint. Vancomycin, one of our strongest antibiotics, has a few strains which are resistant to it.
- Link to National Institute of Health article about use of bacteriophages to battle resistant bacterial infections.
- Link to use of AI to develop antibiotic molecules. This would be a much faster process of drug development as antibiotics were previously very hard to find.
https://www.nih.gov/news-events/nih-research-matters/using-viruses-treat-antibiotic-resistant-bacterial-infections#:~:text=In%20addition%20to%20developing%20novel,engineered%20phages%20along%20with%20antibiotics.
https://med.stanford.edu/news/all-news/2024/03/ai-drug-development.html#:~:text=Stanford%20Medicine%20researchers%20devise%20a,the%20drugs%20in%20the%20lab.
https://www.gov.uk/government/publications/health-matters-antimicrobial-resistance/health-matters-antimicrobial-resistance
https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance#:~:text=Antimicrobial%20Resistance%20(AMR)%20occurs%20when,systems%20and%20national%20economies%20overall.
How has antimicrobial resistance increased between 2017 and 2020?
Another observation was an increase in AMR
rates by more than 15% in 2020 compared with 2017 for: third-generation cephalosporin resistance in bloodstream E. coli infections and azithromycin resistance in gonorrhoea BCIs among others.
