Anti parasitic Drugs Flashcards

1
Q

What is the most common target of antiparasitics?

A

Nervous system

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2
Q

Why use oral?

A

Allows more control over amount of drug given, except feed additives which allow little control

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3
Q

What are topical pour ons and spot ons?

A

Pour ons are for internal and external parasites, spot ons are used in dogs and cats

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4
Q

Name a benzimidazole drug

A

Fenbendazole

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5
Q

Name an Imidazothiazole drug

A

Levamisole

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6
Q

What is levimasole used for?

A

Kill nematodes

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7
Q

Name 2 tetrahydropyrimidines and what they do

A

Pyrantel pomoate/ pyrantel tartrate
Mimics action of Ach, causing paralysis
Kills nematodes

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8
Q

Name 2 macrocyclic lactone drugs and what they’re for

A

Ivermectin, Moxidectin, used for heartworm prevention

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9
Q

What is Profender? Side effects?

A

A combination product used topically in cats to treat hookworm, roundworm and tapeworm
Lethargy, salivation, vomiting, tremors

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10
Q

What does the anticestodal Praziquantel do?

A

Kills cestodes and lung trematodes by disintegrating them and eliminates fleas

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11
Q

What does Fenbendazole kill?

A

Taenia species

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12
Q

What is coccidiosis?

A

Infection of isospora and eimeria that causes intestinal disorders

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13
Q

What helps to keep coccidia in check

A

Providing clean, nutritious feed and water and avoiding overcrowding

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14
Q

Which species should Monensin not be used in?

A

Equine, highly cardiotoxic

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15
Q

Which drug kills giardia and is banned in food animals?

A

Metronidazole

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16
Q

Which drug kills the protozoan Babesia and how?

A

Imidocarb via IM inj.

Has cholinergic effect on protozoa. Can be used in dogs, cats and horses

17
Q

Sarcocystis neurona causes what in horses?

A

Equine protozoal myeloencephalitis

18
Q

What drug is used to treat EPM? How does it work?

A

Pyrimethamine, by inhibiting an enzyme that converts a folic acid used for metabolism in parasites to become inactive

19
Q

Who should not get Ivermectin?

A

Collies (MDR1 gene) and puppies under 6 weeks

20
Q

What are adverse effects of Selamectin?

A

Alopecia at Application site, vomiting, diarrhea

21
Q

What is a 6 month heartworm preventive drug

A

Moxidectin

22
Q

What does Melarsimine do and side effects?

A

Kills adult heartworms. Given IM in epaxial muscles

Nephrotoxic and hepatotoxicity

23
Q

Milbemycin is used to kill what?

A

Microfilaria, hookworms, ascarids and whipworms

24
Q

What does Milbemycin kill?

A

Microfilaria, hookworms, ascarids and whipworms

25
Q

What are 3 types of sprays?

A

Prediluted, yard/kennel and concentrated

26
Q

What is a disadvantage of oral products for ectoparasites?

A

May not kill all stages

27
Q

What is Program/Lufenoron for?

A

Stopping the hatching of flea eggs

28
Q

What is Nitenpyram/Capstar for?

A

Tablet that kills adult fleas in 30 min

29
Q

What is permethrin and imidacloprid/K9 Advantix used for?

A

Killing fleas and ticks, avoid in cats

30
Q

How is fipronil/Frontline given?

A

Topically, but not absorbed into blood