Anatomy Lecture Ch 4 Review Questions Flashcards
What are the four basic tissue types?
epithelial, muscular, connective, nervous
What does epithelial tissue do?
covers body surfaces; lines hollow organs, body cavities and ducts; forms glands; allows body to interact with internal and external environments
What does connective tissue do?
protects and supports the body and its organs, binds organs together, stores energy reserves as fat, helps provide the body with immunity to disease-causing organisms
What does muscular tissue do?
composed of cells specialized for contraction and generation of force which generates heat that warms the body
What does nervous tissue do?
detects changes in a variety of conditions inside and outside the body and responds by generating electrical signals called nerve action potentials that activate muscular contractions and glandular secretions
What is a biopsy?
the removal of a sample of living tissue for microscopic examination
What are cell juntions?
contact points between the plasma membranes of tissue cells
What are the five main types of cell junctions?
tight junctions, adhering junctions, desmosomes, hemidesmosomes, and gap junctions
What is the structure of tight junctions?
consist of weblike strands of transmembrane proteins
What do tight junctions do?
inhibit the passage of substances between cells and prevent the contents of these organs from leaking into the blood or surrounding tissues
Where are tight junctions located?
stomach, intestines, and urinary bladder
What is the structure of adhering junctions?
contain plaque, a dense layer of proteins on the inside of the plasma membrane that attaches both to membrane proteins and to microfilaments of the cytoskeleton
What are cadherins?
transmembrane glycoproteins that insert into the plaque of adhering junctions, partially crossing the intercellular space, and connects to cadherins of an adjacent cell
What are adhesion belts?
extensive zones formed from adhering junctions that encircle the cell
What do adhering junctions do?
help epithelial surfaces resist separation during various contractile activities, such as food moving through the intestines
What is the structure of desmosomes?
contain plaque and have cadherins that extend into the intercellular space between adjacent cell membranes and attach cells to one another; plaque does not attach to microfilaments but instead to intermediate filaments
What are intermediate filaments made of?
the protein keratin
Where are desmosomes most common?
cells that make up the epidermis and among cardiac muscle cells
What is the function of desmosomes?
prevent epidermal cells from separating under tension and cardiac muscle cells from pulling apart during contraction
How are hemidesmosomes different from desmosomes?
they do not link adjacent cells
What are the transmembrane glycoproteins in hemidesmosomes called?
integrins
What do hemidesmosomes do?
anchor cells to the basement membrane but not to one another
What is the structure of gap junctions?
membrane proteins called connexins form tiny fluid-filled tunnels called connexons that connect neighboring cells
What do gap junctions do?
allow ions and small molecules to diffuse from the cytosol of one cell to another through connexons while preventing the passage of large molecules; allow the cells in a tissue to communicate with one another; enable nerve or muscle impulses to spread rapidly among cells
How are cells arranged in epithelial tissue?
tightly packed with little or no extracellular matrix
How are cells arranged in connective tissue?
a large amount of extracellular matrix separates cells that are usually widely scattered
What are the differences in blood vessels between epithelial and connective tissue?
epithelial tissue has no blood vessels; connective tissues have significant networks of blood vessels which contain and distribute almost all the blood vessels in the body
What is epithelial tissue?
consists of cells arranged in continuous sheets, in either single or multiple layers
What are the two general types of epithelial tissue?
surface epithelium and glandular epithelium
What does surface epithelium do?
forms the outer covering of the skin and some internal organs and the inner lining of structures
Where is surface epithelium found besides the skin?
blood vessels, ducts, body cavities, and the lining of the respiratory, digestive, urinary, and genital systems
What does glandular epithelium do?
makes up the secreting portion of glands
Where is glandular epithelium found?
thyroid gland, suprarenal glands, sweat glands, digestive glands
What does epithelial tissue do?
protects, secretes (mucus, hormones, enzymes), absorbs nutrients in the digestive canal, and excretes various substances in the urinary tract
Where is the apical surface of an epithelial cell located?
facing the body surface, a body cavity, the lumen (interior space) of an internal organ, or a tubular duct
Where is the lateral surface of an epithelial cell located?
faces the adjacent cells on either side
What types of junctions do lateral surfaces of epithelial cells contain?
tight junctions, adhering junctions, desmosomes, gap junctions
Where is the basal surface of epithelial cells located?
opposite of the apical surface
What is the basement membrane?
a thin extracellular layer that commonly consists of two layers
What are the two layers of the basement membrane?
basal lamina and reticular lamina
What is the basal lamina?
closest to, and secreted by, the epithelial cells, contains proteins such as laminin and collagen as well as glycoproteins and proteoglycans
What do laminin molecules in the basal lamina do?
adhere to integrins in hemidesmosomes and attach epithelial cells to the basement membrane
What is reticular lamina?
closer to the underlying connective tissue and contains proteins such as collagen produced by fibroblasts in connective tissue
What are the functions of the basement membrane?
attaching to and anchoring the epithelium to its underlying connective tissue, forming a surface along which epithelial cells migrate during growth or wound healing, restrict passage of larger molecules between epithelium and connective tissue, and participate in filtration of blood in the kidneys
What happens when epithelial tissue combines with nervous tissue?
forms special organs for smell, hearing, vision, and touch
What are the 3 types of arrangements in cell layers?
simple epithelium, pseudostratified epithelium, stratified epithelium
What is simple epithelium?
a single layer of cells
What are the functions of simple epithelium?
diffusion, osmosis, filtration, secretion, absorption
What is secretion?
the production and release of substances sch as mucus, sweat, or enzymes
What is absorption?
the intake of fluids or other substances such as digested food from the intestinal tract
What is pseudostratified epithelium?
appears to have multiple layers of cells because the cell nuclei lie at different levels and not all cells reach the apical surface; is actually a simple epithelium because all its cells rest on the basement membrane
What are the functions of pseudostratified epithelium?
cells that do extend to the apical surface may contain cilia, others secrete mucus
What is stratified epithelium?
two or more layers of cells
What is the function of stratified epithelium?
protects underlying tissues in locations where there is considerable wear and tear
What are the 4 types of epithelial cell shapes?
squamous, cuboidal, columnar, transitional
What are squamous cells?
thin, flat cells which allow for the rapid passage of substances through them
What are cuboidal cells?
shaped like cubes or hexagons, may have microvilli at their apical surface and function in either secretion or absorption
What are columnar cells?
shaped like columns, protect underlying tissues, apical surfaces may have cilia or microvilli and are often specialized for secretion or absorption
What are transitional cells?
change shape from squamous to cuboidal and back, as organs of the urinary system such as the bladder stretch and collapse
What are the 4 major types of simple epithelium?
simple squamous epithelium, simple cuboidal epithelium, simple columnar epithelium, pseudostratified columnar epithelium