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RUSVM Pharmacology 2016 > Analgesia > Flashcards

Analgesia Flashcards

1
Q

Lidocaine- receptors and use?

A

Large animal local and systemic anesthetic used to control ventricular arrhythmias, adjunctive analgesia, GI prokinetic, and anti inflammatory

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2
Q

Bupivacaine - use and cautions?

A

Large animal local anesthetic - MOST CARDIOTOXIC

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3
Q

Mepivacaine- use?

A

Diagnostic nerve block in horses

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4
Q

Procaine - cautions

A

Toxic- can cause CNS stimulation - DONT GIVE IV!!

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5
Q

Proparacaine- use?

A

Topical ophthalmic that allows for corneal and conjunctival manipulation

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6
Q

NSAIDs - receptors and use?

A

Inhibit cyclooxygenase enzymes for anti inflammatory, analgesic, antipyretic effects, anti thrombotic effects, and anti neoplastic effects

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7
Q

COX-1

A

Production of prostaglandins that play an important role in normal homeostasis

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8
Q

COX-2

A

Inducible prostaglandins produced during inflammation

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9
Q

COX-1 selective inhibitors

A

Acetylcalicylic acid

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10
Q

non specific COX inhibitors

A

Flunixin
phenylbutazone
ketoprofen

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11
Q

COX-2 preferential inhibitors

A

Deracoxib
Carprofen
Meloxicam

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12
Q

COX-2 selective inhibitors

A

Firocoxib

Robenacoxib

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13
Q

Flunixin Meglumine “Banamine” - use?

A

Soft tissue disease in horses and CATTLE

ONLY NSAID labeled in cattle
DO NOT use in small animal

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14
Q

Phenylbutazone “Bute” - use?

A

Used for musculoskeletal pain in horses

NOT LABELED IN CATTLE!

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15
Q

Carprofen, Meloxicam, Deracoxib - receptors and use?

A

COX-2 preferential for use in small animals as analgesic and anti inflammatory

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16
Q

Firocoxib and Robenacoxib - use?

A

Firocoxib- paste in horses and chewable in dogs

Robenacoxib - ONLY product labeled for multiple IV doses in cats

17
Q

Tramadol - receptors and use?

A

Weak mu agonist and serotonin and norepinephrine reuptake inhibitor, M1 antagonist - used an an oral analgesia

AVOID IN EPILEPTIC PATIENTS!!

18
Q

Gabapentin- receptors and use?

A

Alters the calcium influx in neuronal cells - used for the control of neuropathic pain

19
Q

Amantadine - receptors and use?

A

NMDA antagonist - used as a adjunctive analgesic in small animals

20
Q

Other anti inflammatory & chondroprotective drugs:

A

Glucosamine chondroitin
Polysulfated gylcoaminoglycans
pentosan polysulfate
Omega 3 fatty acids

21
Q

Local anesthetics - mechanism of actions and use?

A

Block the propagation of an action potential by inhibiting the flux of sodium through voltage-dependent sodium channels used for minor procedures, lameness localization, pre-and post analgesia for surgery, operative analgesia, and the treatment of ventricular arrhythmias

RUSVM Pharmacology 2016 (15 decks)

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