Anakinra Flashcards

1
Q

Virkningsmekanisme

A

IL-1-receptor-antagonist.Indiceret ved aktiv, behandlingsresistent reumatoid artritis. Mindre effekt end anti-TNFα- og anti-IL-6-receptor-antistof

Blokerer effekt af proinflammatorisk IL-1.

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2
Q

Anakinra

Dosering

A

Injiceres s.c. gange 1 dgl, veldokumenteret hurtig effekt men mindre effektivt end anti-TNF-behandling.

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3
Q

Anakinra

Bivirkninger

A

Lokale reaktioner ses hyppigt. Infektioner samt granulocytopeni kan forekomme.

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