ADHD: GUANFACINE

Question 1

Cautions

Answer 1

Bradycardia (risk TDP)
Heart block (risk TDP)
History CVD
History QT interval prolongation
Hypokalaemia (risk TDP)

Question 2

Signs of overdose

Answer 2

• hypotension,
• bradycardia
• lethargy
• respiratory depression
  patients who develop lethargy should be observed for development of more serious toxicity for up to 24 hours

Question 3

Guanfacine - contraception

Answer 3

Contraception needed?
effective contraception in females of childbearing potential