ACLS Drugs

Question 1

Drug classification for adenosine

Answer 1

Antidysrhythmic (class V) / Nucleoside

Question 2

MOA for Adenosine

Answer 2

Adenosine (A1) R-agonist - Slow AV conduction by activation of G protein 2nd messenger, decreasing CaMP, and inhibiting calcium entry into the cardiac pacemaker cells

Question 3

Pharmacokinetics for Adenosine

Answer 3

Onset : Immediate
Peak : immediate
Duration : 30-45 seconds
Half : 6 seconds

Question 4

Indications for adenosine

Answer 4

SVT (PSVT) / Narrow Complex Tachycardia
Diagnostic maneuver : stable narrow complex tachycardia
Wide regular monomorphic tachycardia

Question 5

Contraindications for Adenosine

Answer 5

2/3 heart blocks, sick sinus syndrome, polymorphic VT ( Torsades )
Poison / chemical induced SVT ( ex. Cocaine)

Question 6

Side effects for Adenosine

Answer 6

Facial flushing, HA, chest pain, dizziness

Question 7

Adult Dose for Adenosine

Answer 7

1st dose : 6mg rapid IV/IO (proximal vein) followed by 20cc NS flush
2nd dose : 12 mg rapid IV/IO (proximal vein) followed by 20cc NS flush

Question 8

Pediatric dose for adenosine

Answer 8

1st dose : 0.1mg/kg rapid IV/IO (proximal vein) max 6mg

2nd dose : 0.2mg/kg rapid IV/IO max 12mg

Question 9

Trade name for Adenosine

Answer 9

Adenocard