ABSITE Review - Thoracic Flashcards
Where is the azygos vein located and where it drains?
It is located in th eirght side and dumps into SVC
Where is the thoracic duct located and where it drains?
It runs along the right side, crosses midline, and dumps into Left subclavian vein at junction with IJ vein. Crosses at T4-5.
Where runs the vagus and phrenic nerve in relation to the hilum?
Phrenic nerve runs ANTERIOR to the hilum
Vagus nerve runs POSTERIOR to the hilum
What is the function of the Type I and II pneumocytes?
Type I pneumocytes - gas exchange
Type II pneumocytes - surfactant production
What are the needed postop FEV1, DLCO, FVC values?
FEV1 > 0.8 (or at least 40% of the predicted value)
DLCO > 11-12 mL/min/mmHg CO (at least 50%)
FVC > 1.5L
When lung resection is not possible, using the preop pCO2 and VO2?
No resection if preop pCO2 > 45 or pO2 < 50 at rest
No resection if preop VO2 max < 10 mL/min/kg
What is the MC site of lung metastasis?
Brain
What is the MC type of lung cancer?
Adenocarcinoma (non-small cell)
In terms of location, where is most likely to find lung adenocarcinoma vs squamous cell cancer?
Squamous cell - more central
Adenocarcinoma - more peripheral
In terms of lung adenocarcinoma and squamous cell cancer, which has increased risk of local recurrence?
Squamous cell carcinoma
In terms of lung adenocarcinoma and squamous cell cancer, which has increased risk of distant metastases?
Adenocarcinoma
Mention the paraneoplastic lung syndromes.
Squamous cell - PTH-related peptide
Small cell CA - ACTH, ADH
Small cell ACTH - MC paraneoplastic syndrome
What is the most malignant lung tumor? What is the cause?
Mesothelioma - due to asbestos exposure
What is the role of mediastinoscopy?
Use for centrally located tumors and patients with suspicious adenopathy (>0.8cm or subcarinal >1.0cm) on chest CT
What is the Pancoast tumor?
Tumor invades apex of chest wall and patients have Horner’s syndrome.
What is Horner’s syndrome?
Invasion of sympathetic chain –> ptosis, miosis, anhidrosis
What is the next step when a coin lesion is found?
Follow up if no growth in 2 years, smoth contour suggests benign disease
What is the MC benign adult lung tumor? What are theusua CT findings?
Hamartomas - Have calcifications and can appear as a popcorn lesion on chest CT.
What is the MC mediastinal tumor in adults and children?
Neurogenic tumors, usually in posterior mediastinum
What are the common tumor per are of mediastinum?
Anterior - T’s –> thymoma, thyroid cancer or goiter, T-cell lymphoma, Teratoma, Parathyroid adenomas
Middle - Bronchiogenic cysts, pericardial cysts, enteric cysts, lymphoma
Posterior - enteric cysts, neurogenic tumors, lymphoma
What is the 50% rule for thymomas?
50% of thymomas are malignant
50% of patients with thymomas have symptoms
50% of patients with thymomas have myasthenia gravis
10% of patients with myasthenia gravis have thymomas
All thymomas require resection
What is the MC variant of T-cell lymphoma?
Lymphoblastic
What is the MC variant of Hodgkin’s lymphoma?
Nodular Sclerosing
T/F: The MC neurogenic tumor in the mediastinum is the neurolemmoma.
TRUE