ABSITE Review - Plastics Flashcards

1
Q

What are the antigen presenting cells in the skin?

A

Langerhans cells

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2
Q

What type of UV radiation is responsible for chronic sun damage?

A

UV B

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3
Q

What are the risk factors for melanoma?

A

Dysplastic, atypical or large congenital nevi
Familial BK mole syndrome
Xeroderma pigmentosum
Fair complexion, easy sunburn, intermittent sunburns, previous skin cancers, previous XRT

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4
Q

What is the MC melanoma site for men and women?

A

Men - back

Women - legs

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5
Q

Melanoma originates from…

A

neural crest cells (melanocytes) in basal layer epidermis

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6
Q

What is the MC location for distant melanoma metastases?

A

Lung

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7
Q

What is the MC metastases to small bowel?

A

Melanoma

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8
Q

What is the MC type of melanoma?

A

Superficial spreading melanoma

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9
Q

WHat is the most aggressive type of melanoma?

A

Nodular

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10
Q

When you perform a SLN biopsy in melanoma?

A

When melanoma > 1mm deep

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11
Q

What are the Clark’s levels for melanoma?

A
I - epidermis BM intact
II - papillary dermis through BM
III - Junctional dermis between papillary and reticularis dermis
IV - Reticular dermis
V - Fat
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12
Q

What are the margins needed for melanoma resection depending on size?

A

1cm margin
1-4mm –> 2cm margin
>4mm –> 2-3cm margin

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13
Q

What is the MC skin cancer in USA?

A

Basal cell carcinoma

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14
Q

What are the clinical and pathologuc characteristic of basal cell carcinoma?

A

Clinical - Pearly appereance, rolled borders

Pathology - peripheral palisading of nuclei and stromal retraction

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15
Q

T/F: SCC metastisize more often than BCC

A

TRUE

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16
Q

What are risk factors for SCC?

A

actinic keratoses, xeroderma pigmentosum, Bowen’s disease, atrophic epidermis, arsenics, hydrocarbons, chlorophenols, nitrates, HPV, immunosuppresion, sun exposure, fair skin, XRT exposure, previous skin CA

17
Q

What are the two MC soft tissue sarcomas?

A
#1 - malignant fibrous histiosarcoma
#2 - liposarcoma
18
Q

What are the criteria for excisional vs incisional biopsy?

A

Excisional biospy if mass 4cm (may need to eventually resect biopsy skin site if biopsy shows sarcoma)

19
Q

What kind of metastasis is more common in sarcomas?

A

Hematogenous to Lung

20
Q

What are the margins needed for sarcoma resection?

A

3cm margins and at least 1 uninvolved fascial plane

21
Q

Which sarcomas may benefit from preop XRT and chemotherapy?

A

Tumors > 10cm

22
Q

What is the MC sarcoma in children?

A

Rhabdomyosarcoma

23
Q

What is the MC location for a desmoid tumor?

A

Anterior abd wall

24
Q

When a desmoid tumor can occur?

A

During or after pregnancy; can also occur after trauma or surgery

25
Q

In hidradenitis, there is an infection of?

A

Apocrine sweat glands