A1 Understand health issues page 41 Flashcards

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1
Q

What challenges did doctors face with burn injuries during the Second World War?

A

Doctors faced severe burn injuries from crashes and explosions, with many patients dying before the burns could heal.

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2
Q

What techniques did surgeons McIndoe and Gillies pioneer for treating severe burns?

A

McIndoe and Gillies pioneered techniques like saline baths and skin grafting, using grafts with blood supply tubes to help heal severe burns.

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3
Q

What are the limitations of skin grafting surgery?

A

Skin grafts leave significant scars and may fail, requiring additional surgery, and they do not fully replicate natural skin.

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4
Q

How did stem cell research in the 1960s and 1970s impact skin grafting?

A

Stem cell research opened the possibility of growing sheets of skin, though the techniques were limited in success and could not fully regrow skin layers.

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5
Q

Why has it been difficult to fully regrow skin using stem cell techniques?

A

It has been difficult to regrow skin because structures in the lower skin layers, like hair follicles, cannot be reliably reproduced with current stem cell techniques.

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6
Q

What is epigenetics, and what role does it play in gene expression?

A

Epigenetics refers to how genes are switched on or off without changing the underlying genome, influencing processes like cell differentiation and disease.

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7
Q

How might epigenetic changes be linked to environmental factors during pregnancy?

A

Environmental factors like pollution during pregnancy can increase the risk of conditions like asthma in the baby due to epigenetic changes.

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8
Q

What potential does epigenetic research have for preventing diseases in the future?

A

Epigenetic research offers potential for reprogramming genetic code and preventing diseases by understanding how lifestyle and environmental factors affect gene expression.

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