A&P Chapter 16: Flashcards
Hormones
- paracrine glands, e.g. prostaglandins
- autocrine gland, e.g. interleukins
- exocrine glands, e.g. sweat glands
secrete their products into the body fluid (tissue fluid)
paracrine glands
paracrine glands products affects only the surrounding cells
prostaglandins
secretion affects only the secreted cells
autocrine glands, some interleukins
secrete their products into a duct
exocrine glands
excrine glands ducts transport the secreted products
sweat glands
are considered to be endocrine secretion that produce local hormones
paracrine and autocrine secreations
steroid (or steroid like substances) hormones
are lipid soluble
non-steroid hormones
- amines: amino acids
- peptides: groups of amino acids
- proteins: much longer than peptides
- glycoproteins: carbs and protein
- all are water soluble
complex lipid substance
steroid hormones
derive from chloesterol
steroid hormones
these are lipid soluble compound; easily diffuse through the cell membrane
steroid hormone
combine with the receptors inside the nucleus and activate specific genes to synthesize specific proteins
steroid hormone
such proteins produce special effects or functions – which are the hormonal functions
steroid hormone
vitamin – D is a modified steroid that can be converted into a
hormone (Dihydroxycholecalceferol) to promote absorption of calcium and phosphorus in the gut
steroid hormone
examples of steroid hormones
androgen and estrogen
fat soluble hormones
steroid hormone
process of steroid hormones
Hormone passes through the cell membrane → passes through the cytoplasm → passes through the nuclear membrane → binds to a hormone receptor → binds to the DNA → activates gene →
protein synthesis → Protein action is the hormonal action
water soluble hormones
non-steroid hormones
process of non-steroid hormones
hormones bind to receptor and activate G-protein (hormone is the first messanger→ G protein activates enzyme (Adenylate Cyclase) → adelylate cyclase converts ATP into c-AMP (cyclic adenosine monophosphate) (c-AMP is the 2nd messager) → AMP activates set of enzymes (protein kinases) → Ca2+ is the 3rd messenger
also produced from the adrenal medulla form the amino acids
amines
e.g. triiodothyronine (T-3), thyroxine (T-4)
mostly produced from the hypothalamus and posterior part of the pituitary gland
peptide hormones
e.g. anti-diuretic hormone (ADH): contrict blood vessels blood pressure increase
mostly y produced from anterior part of the pituitary gland and the parathyroid gland
parathyroid hormone (PTH)
there are paracrine secretions; can inflame organs
prostaglandins
these are lipids
prostaglandin
produced by the cells in the liver, kidney, heart, lungs, thymus, pancreas, brain, reproductive organs
prostaglandins