A&P 1 Final unit 4 Flashcards
Generic Human Cell
Three common characteristics
-Plasma membrane
-Cytoplasm
-Cytosol
-Organelles
Plasma Membrane
Phospholipid bilayer
-Hydrophilic & hydrophobic
-Membrane proteins
Integral Membrane Proteins
Integrated within plasma membrane
Transport molecules across membrane
Peripheral Membrane Proteins
Attached to surface of plasma membrane
Transporters
channels, pumps and gates move substances across membrane
Receptors
respond to neurotransmitters and hormones
Identity markers
identify “self” to immune cells
Enzymes in peripheral membrane
Catalyze chemical reactions
Anchoring sites peripheral membrane
secure cytoskeleton to membrane
Linkers peripheral membrane
cell-to-cell attachment
Cholesterol
Lipoproteins
Strengthen membrane and stabilize against temperature extremes
Glycolipids
Maintain membrane stability
Located on outer phospholipid region only
Tight junctions
connect adjacent cells by sealing the intercellular space between cells preventing the paracellular movement of solutes, ions and water
Desmosomes
mediate cell-cell contact and strong adhesion.
Gap Junctions
clusters of intercellular channels that allow direct diffusion of ions and small molecules between adjacent cells
Nucleus
Houses DNA and RNA, handles protein production, cell growth and reproduction
Nuclear membrane
Houses the nucleus, phospholipid bilayer
Allows passage in and out of the nucleus
Nucleolus
Produces ribosomes
Dna
Housed in the nucleus, double helix shape
Chromatin
Unwound strands of protein that occurs during protein synthesis
Chromosomes
Coiled DNA, occurs during cellular reproduction
Genes
Coding for specific proteins
Cytoplasm
Contains the cytosol and organelles.
Cytoplasm
Fluid space within the cell that supports the organelles where lots of chemical reactions occur very rapidly
Organelles
“Little organs”
Perform the work of the cell
Eight different organelles, each with specific function
Mitochondria
Produces energy (ATP) preforms aerobic respiration, which involves combusting glucose and oxygen
Ribosomes
Packages of RNA
Involved in protein synthesis
Transcription
Copy of a gene formed from DNA in nucleus
Translation
RNA is translated into Amino acid chains making up a synthesized protein
Bound ribosomes (Rough ER)
Proteins for export, part of membrane, enzymes in lysosomes
Free ribosomes (cytosol)
All other proteins
Rough ER
Site of ribosomal attachment
Transport vesicles shuttle proteins to Golgi apparatus
Smooth ER
Synthesis of carbohydrates, lipids, and steroid hormones
Detoxification
Calcium ion storage
Golgi Apparatus
Sorts and packages macromolecules for cell maintenance, repair and transport
Lysosomes
Immune cells, attacks and dissolves unwanted things
Peroxisomes
Involved in lipid
production
Cytoskeleton
Provides the cell with structural support
Centrosomes
Reorganize the cytoskeleton to move chromosomes to
ensure each daughter cell receives the appropriate
number of chromosomes
Comprised of 2 centrioles
Proteosomes
Eats messed up proteins
Cilia
Protein projections that wave substances past the cell
“mucus elevator”
Flagella
tails that enable things like sperm to swim
Villi
Finger-like projections of cell membrane that increase surface area for absorption
-Small intestine
Passive transport
No cellular energy required
Substances move down concentration gradient
Osmosis and diffusion
Active transport
Requires cellular energy
Substances moved up concentration gradient
Diffusion
-Passive
-Moves from higher to lower concentration uses kinetic energy. A steeper gradient or higher temperature increases diffusion rate
Simple diffusion
Molecules move unassisted between phospholipid molecules. Small and nonpolar solutes. Not regulated by plasma membrane
Facilitated diffusion
Transport process for small charged or polar solutes Requires assistance from plasma membrane proteins
can be channel or carrier mediated
Osmosis
Movement of water, not solutes
Passive movement of water through semipermeable membrane
Osmosis is promoted by differences in water concentration on either side of a membrane
Isotonic solution
ECF and cytosol have same solute concentration
No net movement of water in/out of cell
Hypotonic solution
ECF has lower solute concentration than cytosol
Water moves into cell
Hemolysis
cell ruptures
Hypertonic solution
Solution with higher concentration of solutes than
cytosol
Water moves from inside cell to outside
Crenation
cell shrinks
Active transport process
Solute moves against concentration gradient
Primary and secondary (active) transport
primary uses atp
secondary uses a secondary substance
Vesicular transport
Movement of large substances with vesicle
Move out is exocytosis, moving in is endocytosis
symport
two substances moved in the same direction
antiport
two substances moving In opposite directions
pinocytosis
ingestion into cell via invaginations
phagocytosis
cell eating
exocytosis
contents of a cell vacuole are released outside the cell
Ligands
Chemical messengers released by one cell to signal either itself or a different cell