8.3 Flashcards
transcription
the process of copying DNA into RNA to be used for coding proteins
central dogma
the process of turning genes into proteins
what are the base pairing rules for RNA
A and U
C and G
what are some similarities between RNA and DNA
DNA:
- deoxyribose
- T base
- double stranded
- stores information
RNA:
- ribose
- U base
- single stranded
- making proteins
BOTH:
- sugars
- bases A, G, C
- phosphate group
enhancer
controls if/how much RNA is made
promoter
start site of transcription, signals TFs and RNA Pol. to attach
exons
sequences that will be present in mRNA
introns
sequences that will be cut out
initiation
transcription factors bind to promoter and attract and prepare RNA Pol. to begin copying gene sequence into mRNA
elongation
RNA Pol breaks free of TFs, a protective 5’ cap is added to RNA so that the protein doesn’t get digested by DNA Pol. I, as RNA Pol. copies DNA, their proteins are used to splice out introns
termination
at polyadenylation site the termination sequence is recognized and cut, a PolyA tail is added to tell when to destroy the mRNA, the longer the A tail, the longer it makes proteins, and the shorter it gets. when it runs out, the RNA molecule is destroyed so no more proteins are made with it
what happens during the splicing process
the introns are spliced out of the RNA
what happens during alternative splicing
- one gene can code for multiple proteins
- cuts out different sequences of introns and the different sequences of exons creates different proteins