8. Organisation of the Peripheral Nervous System Flashcards
Define DERMATOME and MYOTOME
Dermatome: a SLICE of SKIN
Myotome: a SLICE of MUSCLE
which SPINAL ROOT is SENSORY (and where is it going into)
DORSAL / POSTERIOR
into DORSAL / ALAR HORNS of GREY MATTER - pointy
which SPINAL ROOT is MOTOR (and where is it coming from)
VENTRAL / ANTERIOR
from VENTRAL / BASAL HORNS of GREY MATTER
which part of PNS is in ROSTRO-CAUDAL AXIS (top to bottom)
CRANIAL NERVES
in PNS SPINAL NERVE ROOT -> SPINAL NERVE for OVER THE TRUNK
how is it for LIMBS
ROOT -> PLEXUS -> NERVE
Name the 2 GANGLIA of the PNS
- DORSAL ROOT GANGLION : where cell bodies of sensory neurones are
- AUTONOMIC GANGLION (SYMPATHETIC) : contains cell bodies of the post ganglionic autonomic axon
(contain the ONLY SYNAPSES in the PNS)
SENSORY system uses what type of nerve cells
UNIPOLAR cells in the DRG
MOTOR system uses what
(ALPHA) MOTOR NEURON in the ANTERIOR / VENTRAL HORN
AUTONOMIC system uses what
AUTONOMIC GANGLIA and PRE/POST FIBRES
where is the place that has the ONLY SYNSAPSES in the PNS
AUTONOMIC GANGLIA
which CRANIAL NERVES arise from the BRAINSTEM
therefore these are PERIPHERAL
3 - 12
Occulomotor
Trochlear
Trigeminal
Abducens
Facial
Vestibulocochlear
Glossopharyngeal
Vagus
Accessory
Hypoglossal
(all EXCEPT Olfactory and Optic)
which CRANIAL NERVES come from the MIDBRAIN
3 & 4
OCCULOMOTOR & TROCHLEAR
(eye movement)
which CRANIAL NERVES come from the PONS
5, 6, 7, 8
TRIGEMINAL, ABDUCENS, FACIAL, VESTIBULOCOCHLEAR
which CRANIAL NERVES come from the MEDULLA
9, 10, 11, 12
GLOSSOPHARYNGEAL, VAGUS, ACCESSORY, HYPOGLOSSAL
where does FACIAL NERVE arise from
PONS
where does TROCHLEAR NERVE arise from
MIDBRAIN
where does VAGUS NERVE arise from
MEDULLA
where does ABDUCENS NERVE arise from
PONS
where does TRIGEMINAL NERVE arise from
PONS
where does the GLOSSOPHARYNGEAL NERVE arise from
MEDULLA
where does VESTIBULOCOCHLEAR NERVE arise from
PONS
MIDBRAIN consists of what for processing
- CORTICOSPINAL TRACTS,
- S. NIGRA
- AUDITORY & VISUAL REFLEX CENTRES
PONS consists of what for processing
CEREBRO-CEREBELLAR RELAYS
also Apneustic and Pneumotaxic centres for respiration
MEDULLA consists of what for processing
- LONG TRACTS
- RESPIRATORY and CARDIAC CENTRES
what GANGLIA are CRANIAL (not in PNS)
- SENSORY GANGLIA (drg equivalents)
- PARASYMPATHETIC GANGLIA (pns has sympathetic)
what does RAMUS mean
BRANCH
RAMI of the SPINAL NERVE that come after the roots
VENTRAL RAMI (important) - lateral and ventral (anterior)
DORSAL RAMI - supplies skin and muscles of the back (posterior)
what GANGLIA exist on VENTRAL ROOTS
AUTONOMIC GANGLION
aka SYMPATHETIC GANGLION
AUTONOMIC (SYMPATHETIC) GANGLION CONNECT to the SPINAL ROOTS via which ADDITIONAL RAMI
RAMI COMMUNICATES
- can be WHITE RAMI (more myelinated) or GREY RAMI
what do RAMI COMMUNICATES do (white or grey)
CONNECT the SYMPATHETIC GANGLION to the SPINAL ROOTS
example of a PLEXUS: BRACHIAL PLEXUS
what are the SPINAL ROOTS
C5-T1
C5,C6,C7,C8,T1
NERVES that arise from the BRACHIAL PLEXUS (C5-T1)
- RADIAL NERVE
wrist and finger Extensors - MEDIAN NERVE
muscles of Thenar Eminence (base of thumb) and lateral hand sensation - ULNAR NERVE
most muscles of Hand, Medial hand sensation
also MUSCULOCUTANEOUS,
Cutaneous nerves of arm/forearm
Axillary nerve
NERVES that arise from the LUMBAR SACRAL PLEXUS
- FEMORAL NERVE (L2-L4)
knee Extension, Anterior thigh sensation - SCIATIC NERVE (L4-S2)
Hip Extension, Knee Flexion
branches:
-> COMMON PERONEAL / FIBULAR NERVE
Ankle Dorsiflexion & Eversion, Lateral Leg sensation
-> TIBIAL NERVE
Ankle Plantarflexion & Inversion
LAYER SURROUNDING the AXONS in a nerve:
ENDONEURIUM
LAYER SURROUNDING the FASCICLES (bundles of axons) in a nerve:
PERINEURIUM
OUTERMOST LAYER that SURROUNDS PERIPHERAL NERVES
INTERNAL & EXTERNAL EPINEURIUM
how are SCHWANN CELLS in MYELINATED AXONS
series of schwann cells LINED UP ALONG the AXON
each one having a WRAPPED COATING of MYELIN insulating the axon
- each AXONAL SEGMENT is ENCASED in WRAPPED LAYERS of LIPID MEMBRANE of the SCHWANN CELL
how are SCHWANN CELLS in UNMYELINATED AXONS
unmyelinated axons in PNS are ENCASED BY SCHWANN CELL CYTOPLASM
but no wrapped coating of myelin surround axons
- SUPPORTED BY SCHWANN CELLS
how do DIVIDE NERVES into TYPES
by their…
- FUNCTION
- DIRECTIONALITY (Afferent or Efferent)
- MYELINATION STATUS
- AXONAL DIAMETER - A, B, C Fibres
how are A NERVE FIBRES
LONGEST DIAMETER
MYELINATED
FAST
- alpha, beta, gamma (efferent) and delta (afferent) types
how are B NERVE FIBRES
SMALL DIAMTER (middle)
MYELINATED
*SLOW
mostly PRE-GANGLIONIC AUNTONOMIC FIBRES
how are C NERVE FIBRES
SMALLEST DIAMETER
*UNMYELINATED
FAST
mostly POST-GANGLIONIC ANS
and some PAIN fibres - SLOW PAIN
PRE-GANGLIONIC ANS FIBRES are normally what type
B
small, myelinated, slow
POST-GANGLIONIC ANS FIBRES are normally what type
C
smallest, unmyelinated, slow
which NERVE FIBRES transmit SLOW PAIN
C FIBRES
what type of NEURONS are used in PNS SENSORY SYSTEM
PSEUDOUNIPOLAR DRG Neurons
Cell Bodies as an expansion of the Dorsal Root
PNS SENSORY SYSTEM.
PROXIMAL BRANCHES of DRG NEURON enter either:
- DORSAL (posterior) COLUMN OF CORD (white matter)
dosal column/medial lemniscus pathway
carries complex somatosensory information ie movement
ASCENDS - DORSAL (posterior) HORN OF CORD (white matter)
Spinothalamic pathway, 2nd order neuron
where are CUTANEOUS RECEPTORS and what are they
SENSORY RECEPTORS in the SKIN
that permit a range of SOMATOSENSORY SUB-MODALITIES to be DETECTED
those CUTANEOUS RECEPTORS that DETECT MOVEMENT have RAPIDLY-ADAPTING SIGNAL TRANSDUCTION PATHWAYS and transmit it to the CNS VIA…
FAST ABETA AFFERENTS
- well myelinated
those CUTANEOUS RECEPTORS that TRANSMIT SUBMODALITIES ie PAIN use what..
SMALLER AXONS
SLOW NOCICEPTIVE FREE ENDINGS that transmit via C-FIBRES
- to encourage animal to protect an injured part
MOTOR NEURON CELL BODIES are LOCATED where
in the VENTRAL (anterior) HORN of the GREY MATTER of the cord
their AXONS transverse the White Matter of cord, form BUNDLES (FASCICLES) and then EXIT the cord as a VENTRAL ROOT
VENTRAL & DORSAL ROOTS JOIN after the DRG at the exit point of the INTERVERTEBRAL FORAMEN
the MUSCLES CORRESPONDING to a SPINAL CORD are a..
MYOTOME
what is a MOTOR UNIT (consist of)
a MOTOR NEURON, its AXON, AXONAL BRANCHES, their TERMINATIONS and CONNECTED MYOFIBRILS
HIGHER BRAIN CENTRES (CNS) influence the OUTPUT of PARASYMPATHETIC ANS
- major play in this is the…
HYPOTHALAMUS
where are the CELL BODIES of the PREGANGLIONIC NEURONS in the PARASYMPATHETIC NERVOUS SYSTEM
in the CRANIAL NERVE NUCLEI
in the BRAINSTEM and SACRAL CORD
(autonomic fibres are particularly in cranial nerves 3, 7, 9, 10 nuclei)
where are the CELL BODIES of the PREGANGLIONIC NEUROS in the SYMPATHETIC NERVOUS SYSTEM
in the CENTRAL GREY - INTERMEDIOLATERAL HORN
in CERVICAL, THORACIC & LUMBAR REGIONS
which REGIONS have the LATERAL HORN on the CENTRAL GREY
CERVICAL
THORACIC
LUMBAR
the MOST ROSTAL (superior) SYMPATHETIC OUTFLOW is at what spinal level
T1
(parasympathetic is higher)
what are in the VENTRAL HORNS of CENTRAL GREY
MOTOR NEURON CELL BODIES
how are the CAROTID ARTERY and the VAGUS NERVE OPPOSITE?
CAROTID ARTERY - Carries SYMPATHETIC outflow UP to head
VAGUS NERVE - Carries PARASYMPATHETIC outflow DOWN from brainstem
how does CAROTID ARTERY carry SYMPATHETIC OUTFLOW (from, to..) in its wall
FROM THORACIC CORD
- TO HEAD
UP
how does VAGUS NERVE carry PARASYMPATHETIC OUTFLOW (from, to..)
FROM BRAINSTEM
- TO TRUNK
DOWN
where is SYMPATHETIC OUFLOW FROM in the CAROTID ARTERY
from THORACIC TRUNK up to head
AFFERENTS can also exist from .. as ..
INTERNAL ORGANS as VISCERAL AFFERENTS
where are the PRE-GANGLIONIC NEURONS in the SYMPATHETIC vs PARASYMPATHETIC
Sympathetic: CERVICAL, THORACIC, LUMBAR Cord
(THORACO-LUMBAR OUTFLOW)
Parasympathetic: BRAINSTEM (mostly) and SACRAL CORD
where are SYMPATHETIC GANGLIA vs PARASYMPATHETIC GANGLIA
And so how are their PRE-GANGLIONIC FIBRE LENGTHS?
Sympathetic: NEAR CNS
Parasympathetic: NEAR/WITHIN the END ORGAN (not near CNS)
Sympathetic: SHORT PRE-GANGLIONIC
Parasympathetic: LONG PRE-GANGLIONIC (post-ganglionic are short)
POST GANGLIONIC NEURONS use what CHEMICAL in SYMPATHETIC vs PARASYMPATHETIC
Sympathetic: NORADRENERGIC (noradrenaline)
Parasympathetic: CHOLINERIC (Acetylcholine)
(act as MUSCARINIC RECEPTORS)
what use FAST ABETA AFFERENTS
CUTANEOUS RECEPTORS that transmit the DETECTION OF MOVEMENT