11. Motor II - the CEREBELLUM, feedback and feedforward Flashcards

1
Q

FUNCTION of the CEREBELLUM

A

CALIBRATES the PRECISION OF ACTION

  • functions as an ERROR DETECTOR

had Feedback (if movement goes wrong to inhibit in the future) and Feedforward processing to IMPROVE ACCURATY of FUTURE MOVEMENTS

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2
Q

LACK of FUNCTION in the CEREBELLUM leads to..

A

CLUMSINESS
- ATAXIA (disordered movement)
or
- DYSMETRIA (badly measured movement)

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3
Q

what are the ASCENDING TRACTS

A

DORSAL COLUM

SPINOCEREBELLAR TRACT

SPINOTHALAMIC TRACT

(sensory)

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4
Q

what are the DESCENDING MOTOR TRACTS

A

*CORTICOSPINAL
(pyramidal corticospinal tract)

RETICULOSPINAL

VESTIBULOSPINAL

TECTOSPINAL

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5
Q

where is the CEREBELLUM LOCATED is an OUTGROWTH of what

A

the METENCEPHALON / PONS

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6
Q

the CORTICAL SURFACE of the Cerebellum is expanded by FOLDS called..

A

FOLIA

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7
Q

CEREBELLUM is estimated to have 10X MORE NEURONS than the Cerebral cortex.
largely due to its HIGH DENSITY of which cells

A

GRANULAR CELLS

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8
Q

CEREBELLUM is POSTERIOR to the PONS and which VENTRICLE

A

4TH VENTRICLE

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9
Q

which PEDUNCLE connects CEREBELLUM to the PONS and what feedback is it for

A

MIDDLE CEREBELLAR PEDUNCLE

aka BRACHIUM PONTIS

  • for INPUT from CORTEX
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10
Q

where is the CEREBELLUM in relation to the MIDBRAIN and what are they CONNECTED by

A

INFERO-POSTERIOR to midbrain

  • SUPERIOR CEREBELLAR PEDUNCLE
    aka BRACHIUM CONJUNCTIVUM
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11
Q

SUPERIOR CEREBELLAR PEDUNCLE / BRACHIUM CONJUCTIVUM is for what between CEREBELLUM and MIDBRAIN

A

OUTPUT TO THALAMUS (& RED NUCLEUS)

  • Decussates
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12
Q

where is the CEREBELLUM in relation to the MEDULLA and what are they CONNECTED by

A

SUPERO-POSTERIOR to medulla

  • INFERIOR CEREBELLAR PEDUNCLE
    aka RESTIFORM BODY
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13
Q

INFERIOR CEREBELLAR PEDUNCLE / RESTIFORM BODY is for what between CEREBELLUM and MEDULLA

A

INPUT FROM SPINAL CORD PROPRIOCEPTIVE CENTRES

  • from DORSAL SPINOCEREBELLAR TRACT
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14
Q

which connection of the CEREBELLUM to the BRAIN STEM is for INPUT FROM DORSAL SPINOTHALAMIC TRACT from spinal cord PROPRIOCEPTIVE centre

A

INFERIOR PEDUNCLE from MEDULLA

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15
Q

which connection of the CEREBELLUM to the BRAIN STEM is for OUTPUT to the THALAMUS

A

SUPERIOR PEDUNCLE to the MIDBRAIN

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16
Q

MIDDLE CEREBRAL PEDUNCLE AKA

A

BRACHIUM PONTIS

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17
Q

what happens to the Feedback fibres between the CEREBELLUM and CEREBRAL CORTEX in Middle peduncle INPUT and Superior Peduncle OUTPUT

A

DECUSSATE

  • upper part of the BRAIN controls OPPOSITE SIDE of the body
    but CEREBELLUM helps coordination of movement on the SAME SIDE
18
Q

which fibres have UNCROSSED INPUT to CEREBELLUM

A

DORSAL SPINOCEREBELLAR TRACTS from spinal cord via the INFERIOR PEDUNCLE (restiform body) from Medulla to Cerebellum

19
Q

CEREBELLAR SYNDROMES are on the same or opposite side of the body?

A

IPSILESIONAL

  • on the SAME SIDE of the body as the cerebellar LESION
20
Q

what is the OLDEST part of the CEREBELLUM

A

VESTIBULOCEREBELLUM
aka FLOCCULONODULAR LOBE
aka ARCHICEREBELLUM

(dangling at bottom)

21
Q

VESTIBULOCEREBELLUM aka FLOCCULONODULAR LOBE
aka ARCHICEREBELLUM is for what function

A

BALANCE & EYE MOVEMENT

  • connects to vestibular system and vestibular Nuclei (in brainstem)
22
Q

2nd oldest part of the Cerebellum that is found in the midline area is the SPINOCEREBELLUM aka PALEOCEREBELLUM. it connects to the SPINAL CORD via..

A

MEDIAL DESCENDING and LATERAL DESCENDING PATHWAYS

via the THALAMUS

(somatotopic, ipsilateral)

23
Q

what is the LARGEST PART of the Cerebellum that connects to the FRONTAL LOBE anterior to the primary motor cortex (via THALAMUS)

A

CEREBO-CEREBELLUM aka NEOCEREBELLUM

24
Q

CEREBELLAR FOLIA contains what in the CENTRE/CORE?

and what are the LAYERS going out

A

centre WHITE MATTER

-> GRANULE CELLS (GRANULAR LAYER)
-> PURKINJE CELLS and their DENDRITIC TREES (Purkinje Layer)
-> MOLECULAR LAYER (contains axons of the granule and purkinje cells)

25
Q

STAIN used to see histology of Cerebellum

A

H&E

26
Q

INPUT from which fibres form SYNAPSES with GRANULE CELLS in the Granular Layer

A

MOSSY FIBRES

(from brain stem nuclei and spinal cord)

27
Q

INPUT from where forms SYNAPSES with PURKINJE CELLS

A

INFERIOR OLIVARY NUCLEUS

  • comes from the OLIVE of the MEDULLA

connects to purkinje via CLIMBING FIBRES

28
Q

PURKINJE CELLS (large) have a vast DENDRITIC TREE in the Molecular Layer.

how do the GRANULAR CELLS INTERACT with MANY purkinje cell DENDRITIC TREES

A
  • Axons enter MOLECULAR LAYER
  • form Long PARALLEL FIBRES which are perpendicular to the plane of the purkinje cells (dendritic trees)
29
Q

GRANULE CELLS make how many CONNECTIONS with PURKINJE CELLS?

INFERIOR OLIVARY NUCLEUS (of Medulla) makes how many CONNECTIONS with PURKINJE CELLS

A

Granule cells: MANY

ION: ONLY ONE CONNECTION

30
Q

GRANULE CELLS receive INPUT from…

A

MOSSY FIBRES

(non-ION inputs)

31
Q

what is the OUTPUT from the PURKINJE CELL

A

INHIBITORY AXON sent to DEEP CEREBELLAR NUCLEUS to the BRAINSTEM
to descending motor tracts

32
Q

which INPUT is an ERROR SIGNAL, sent when a MOVEMENT goes WRONG (signals a motor error)

A

INFERIOR OLIVARY NUCLEUS inputs

(from MEDULLA)

33
Q

what is known as LONG-TERM DEPRESSION

A

the CO-FIRING of both GRANULE and ION fibres (parallel and climbing fibres)
SUPPRESSES THE PURKINJE CELL

Synapses weaken so in the future would need more excitation to stimulate

  • involves Ca2+ Signalling
34
Q

how does INFERIOR OLIVARY NUCLEUS connect to PURKINJE CELL
via..

A

CLIMBING FIBRE

1 connection

35
Q

how does GRANULAR CELL connect to PURKINJE CELL

via..

A

PARALLEL FIBRE

36
Q

what involves CA2+ SIGNALLING

A

LONG TERM DEPRESSION

where CO-FIRING SUPPRESSES PURKINJE CELL

37
Q

INPUT of the INFERIOR OLVIARY NUCLEUS (MEDULLA)

A

ERROR SIGNAL

38
Q

LIMB MOVEMENT accuracy by which tract

A

SPINOCEREBELLUM

39
Q

EYE MOVEMENT and BALANCE accuracy by which tract

A

VESTIBULOCEREBLLUM

40
Q

what are FOLIA

A

FOLDS on the CORTICAL SURFACE of CEREBELLUM

41
Q

what is BRACHIUM CONJUNCTIVUM

A

SUPERIOR CEREBELLAR PEDUNCLE

that connects Cerebellum to the MIDBRAIN

(decussate)

42
Q

INPUT from MEDULLA (SPINOCEREBELLAR TRACT) is decussated or uncrossed

A

UNCROSSED