8 Flashcards
order of nicotine products from fastest onset to slowest
cigarette > spray > inhaler > lozenge >gum > patch
which gene involved in opioid addiction relapse?
ALDH5A1
2 meds approved for comorbid PTSD and SUD
sertraline
paroxetine
genes involved in alcohol flushing
ALDH2, GABRA2, GABRA6
newborns born to mothers on short acting opioids can be discharged from the hospital after ___ days to assess for w/d
3
newborns born to mothers on long acting opioids can be discharged from the hospital after ___ days to assess for w/d
5-7
drugs with 1st degree kinetics reach steady state after ___ half lives
5
what is the most important factor in zero order kinetics to determine concentration?
dose
what percent of inmates with SUD receive treatment?
11%
is nicotine absorbed more in acidic or basic environments?
basic (like the mouth)
is nicotine absorbed faster through smokeless tobacco like chew or inhaled?
inhaled
at first exposure, peak euphoric effects of marijuna are at ____ min and last _____ hours
30 min
2-4 hours
does cannabis or tobacco carry more tar?
cannabis - 3x more!
community reinforcement approach to sobriety is based on
operant conditioning - rewarding good behavior
single use of marijuana shows up on urine is typically
2 days
using what drug and TCAs can cause tachycardia?
marijuana (beta adrenergic effect of mj + anticholinergic of TCA)
how do acamprosate levels change when given with naltrexone?
increase
when orally ingesting cannabis, peak effect felt after ____ and lasts ____
peak 2 hrs
last 6-8 hrs
which gene involved with cocaine addiction and changes in circadian rhythm?
PER1
name of a test to assess for alcohol abuse in the elderly?
MAST-G (Michigan Alcohol Screening Test - Geriatric Version)
nicotine’s effects on skeletal muscles
relaxant
