8 Flashcards

1
Q

order of nicotine products from fastest onset to slowest

A

cigarette > spray > inhaler > lozenge >gum > patch

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2
Q

which gene involved in opioid addiction relapse?

A

ALDH5A1

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3
Q

2 meds approved for comorbid PTSD and SUD

A

sertraline
paroxetine

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4
Q

genes involved in alcohol flushing

A

ALDH2, GABRA2, GABRA6

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5
Q

newborns born to mothers on short acting opioids can be discharged from the hospital after ___ days to assess for w/d

A

3

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6
Q

newborns born to mothers on long acting opioids can be discharged from the hospital after ___ days to assess for w/d

A

5-7

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7
Q

drugs with 1st degree kinetics reach steady state after ___ half lives

A

5

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8
Q

what is the most important factor in zero order kinetics to determine concentration?

A

dose

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9
Q

what percent of inmates with SUD receive treatment?

A

11%

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10
Q

is nicotine absorbed more in acidic or basic environments?

A

basic (like the mouth)

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11
Q

is nicotine absorbed faster through smokeless tobacco like chew or inhaled?

A

inhaled

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12
Q

at first exposure, peak euphoric effects of marijuna are at ____ min and last _____ hours

A

30 min

2-4 hours

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13
Q

does cannabis or tobacco carry more tar?

A

cannabis - 3x more!

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14
Q

community reinforcement approach to sobriety is based on

A

operant conditioning - rewarding good behavior

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15
Q

single use of marijuana shows up on urine is typically

A

2 days

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16
Q

using what drug and TCAs can cause tachycardia?

A

marijuana (beta adrenergic effect of mj + anticholinergic of TCA)

17
Q

how do acamprosate levels change when given with naltrexone?

A

increase

18
Q

when orally ingesting cannabis, peak effect felt after ____ and lasts ____

A

peak 2 hrs

last 6-8 hrs

19
Q

which gene involved with cocaine addiction and changes in circadian rhythm?

A

PER1

20
Q

name of a test to assess for alcohol abuse in the elderly?

A

MAST-G (Michigan Alcohol Screening Test - Geriatric Version)

21
Q

nicotine’s effects on skeletal muscles

A

relaxant