14 Flashcards

1
Q

alcohol metabolized with what order kinetic

A

zero

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2
Q

is a single item question as sensitive as a 10 item DAST questionnaire for assessing SUDs?

A

yes

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3
Q

which vitamin is deficient in a guy with AUD with nystagmus, wide leg gait

A

thiamine

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4
Q

which B vitamin is thiamine?

A

B1

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5
Q

what does T-ACE questionnaire stand for?

A

Tolerance
Annoyed
Cut down
Eye opener

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6
Q

how much caffeine in a 12 oz cup of coffee

A

200-260mg

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7
Q

how much caffeine in an espresso?

A

70mg

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8
Q

how much caffeine in a 12 oz cup of mountain dew

A

55mg

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9
Q

how much caffeine in 6oz of tea

A

40mg

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10
Q

how much caffeine in a 16 oz monster energy drink

A

160mg

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11
Q

what age group has smallest gender gap for SUDs?

A

12-17 y/os

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12
Q

how many items in AUDIT (not AUDIT-C) and what’s the score to be positive for AUD?

A

10 items

score ≥15

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13
Q

what percent of meth users with chest pain progress to have an MI?

A

25%

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14
Q

what is the mechanism of renal dz in AUD?

A

hepatorenal syndrome- secondary to liver dz

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15
Q

heavy drinking and binge drinking rates in US from 2018

A

6-7% heavy

24% binge

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16
Q

does Bupe affect HAART?

A

no

17
Q

does HAART affect bupe?

A

yes- protease inhibitors inhibit CYP 450 - need dose reduction of bupe

18
Q

how many ounces of malt liquor is a standard drink?

A

8 oz

19
Q

how much alcohol is in a standard drink?

A

14 g or 0.6 oz of alcohol

20
Q

which survey reports higher estimate of drug use - Monitoring the Future Study or National Survey on Drug use? And what are the major differences?

A

Monitoring the Future Study has higher estimates - school conducted study in grades, 8, 10, 12 that describes drug use and beliefs

NSDUH - household survey

21
Q

CYP2A*7 is associated with increased or decreased nicotine clearance?

A

decreased

22
Q

what is the name of the org that establishes standards of care in health care system?

A

National Quality Forum (NQF)

23
Q

CB1 and CB2 receptors are what type of receptors?

A

G couple protein receptors

24
Q

where is CB1 found?

A

brain, liver, adipose tissue, cardiac tissue, reproductive tissue, bone

25
Q

where is CB2 mainly found

A

white blood cells, tonsils, spleen

26
Q

Rimonabant moa and function

A

CB1 rec blocker (inverse agonist)

anti obesity - reduce appetite

27
Q

SB-277011-A is a medication type of what

A

D3 antagonist - promise for addiction

28
Q

alcohol seizures occur within what time frame most likely

A

12-48 hrs

29
Q

men or women more likely to have marital consequences from gambling?

A

men

30
Q

is venlafaxine considered 1st like to treat neuropathic pain?

A

yes apparently so (also duloxetine, TCAs, gabapentin, pregabalin, topical lidocaine)

31
Q

is topiramate considered 1st like to treat neuropathic pain?

A

no, 3rd line

32
Q

do men or women have higher AUD remission rates?

A

women

33
Q

Krokodil is ….

A

desormorphine - synthetic morphine

34
Q

though white people use more drugs, are they less prone to dependence than blacks and hispanics?

A

yes

35
Q

increased body temp is a symptom of which withdrawal syndrome?

A

cocaine or any stimulant