14 Flashcards
alcohol metabolized with what order kinetic
zero
is a single item question as sensitive as a 10 item DAST questionnaire for assessing SUDs?
yes
which vitamin is deficient in a guy with AUD with nystagmus, wide leg gait
thiamine
which B vitamin is thiamine?
B1
what does T-ACE questionnaire stand for?
Tolerance
Annoyed
Cut down
Eye opener
how much caffeine in a 12 oz cup of coffee
200-260mg
how much caffeine in an espresso?
70mg
how much caffeine in a 12 oz cup of mountain dew
55mg
how much caffeine in 6oz of tea
40mg
how much caffeine in a 16 oz monster energy drink
160mg
what age group has smallest gender gap for SUDs?
12-17 y/os
how many items in AUDIT (not AUDIT-C) and what’s the score to be positive for AUD?
10 items
score ≥15
what percent of meth users with chest pain progress to have an MI?
25%
what is the mechanism of renal dz in AUD?
hepatorenal syndrome- secondary to liver dz
heavy drinking and binge drinking rates in US from 2018
6-7% heavy
24% binge
does Bupe affect HAART?
no
does HAART affect bupe?
yes- protease inhibitors inhibit CYP 450 - need dose reduction of bupe
how many ounces of malt liquor is a standard drink?
8 oz
how much alcohol is in a standard drink?
14 g or 0.6 oz of alcohol
which survey reports higher estimate of drug use - Monitoring the Future Study or National Survey on Drug use? And what are the major differences?
Monitoring the Future Study has higher estimates - school conducted study in grades, 8, 10, 12 that describes drug use and beliefs
NSDUH - household survey
CYP2A*7 is associated with increased or decreased nicotine clearance?
decreased
what is the name of the org that establishes standards of care in health care system?
National Quality Forum (NQF)
CB1 and CB2 receptors are what type of receptors?
G couple protein receptors
where is CB1 found?
brain, liver, adipose tissue, cardiac tissue, reproductive tissue, bone
where is CB2 mainly found
white blood cells, tonsils, spleen
Rimonabant moa and function
CB1 rec blocker (inverse agonist)
anti obesity - reduce appetite
SB-277011-A is a medication type of what
D3 antagonist - promise for addiction
alcohol seizures occur within what time frame most likely
12-48 hrs
men or women more likely to have marital consequences from gambling?
men
is venlafaxine considered 1st like to treat neuropathic pain?
yes apparently so (also duloxetine, TCAs, gabapentin, pregabalin, topical lidocaine)
is topiramate considered 1st like to treat neuropathic pain?
no, 3rd line
do men or women have higher AUD remission rates?
women
Krokodil is ….
desormorphine - synthetic morphine
though white people use more drugs, are they less prone to dependence than blacks and hispanics?
yes
increased body temp is a symptom of which withdrawal syndrome?
cocaine or any stimulant
