10 Flashcards
monozygotic vs dizygotic rates of cannabis use disorder
mono: 28%
di: 9%
is college athletics associated with drinking?
yes
increased metabolism of a drug after repeated administration is called
pharmacokinetic tolerance
does avoidant coping mechanisms help predict success or failure in AA?
success
half life of nicotine
2 hours
hepatitis presentation in someone with AUD
fever, leukocytosis, RUQ pain
nicotine withdrawal peaks at what time after last cigarette?
24-48 hours
nalmefene moa and use
treat AUD
mu and delta opioid receptor antagonist with some partial agonist activity at kappa receptor
benefit of nalmefene over naltrexone
does not cause hepatotoxicity
what is best studied and validated instrument for studying alcohol addiction?
Addiction severity index by the treatment research institute
which opioids are not detected on UDS?
hydrocodone, oxycodone
which opioids are detected on standard UDS?
metabolites of morphine, so heroin and codeine
what’s the range of caffeine in energy drinks
100-500mg
which HIV drug will increase methadone dose?
zidovudine
GABA A receptor subunit functions
α1 = sleep
α2 and 3 = anxiety
α4 and 6 = benzo insensitive