15

Question 1

Side effects to naltrexone

Answer 1

nausea
anorexia
abdominal pain
fatigue, insomnia, daytime sleepiness
headache
reversible hepatotoxicity

Question 2

in odds ratio, if the confidence interval crosses ____, then it’s not statistically significant

Answer 2

1

Question 3

which gene involved with increased risk of smoking and interaction with pharmacotherapy in smokers?

Answer 3

CHRN5

Question 4

mean treatment length for detox inpatient vs outpatient

Answer 4

outpatient - 6.5 days

Inpatient - 9.2 days

Question 5

when should phenobarbital be used for neonatal abstinence syndrome?

Answer 5

seizures
polydrug withdrawal
non-opiate withdrawal
received max of opium

Question 6

peak euphoric effect from marijuana inhaled at

Answer 6

30 min

Question 7

probability of becoming dependent on tobacco after one use?

Answer 7

32%

Question 8

NIDA quick screen is how many questions?

Answer 8

one

Question 9

NSAIDs can be false positive for

Answer 9

marijuana

Question 10

is genetic transmission of SUDs mendelian pattern?

Answer 10

no

Question 11

does zidovudine have an effect on methadone levels?

Answer 11

no, just other way around

Question 12

which gene is involved with people who get respiratory depression from codeine (and have european ancestry)?

Answer 12

CYP2D6

Question 13

nicotine metabolized by

Answer 13

CYP2A6

Question 14

do black people or white people absorb more nicotine?

Answer 14

black people - 30% more

Question 15

which ethnicity have lower clearance of nicotine compared to white people?

Answer 15

asians - slower CYP2A6 metabolism

Question 16

volume of distribution of smoking tobacco

Answer 16

180L

Question 17

are benzos CYP 450 inducers?

Answer 17

no

Question 18

how long is duration of cocaine when smoked versus snorted?

Answer 18

smoked: 20-30 min

snorted: 1-3 hours

Question 19

what is this disorder - memory loss, confusion, drowsiness, poor balance, loss of spontaneity

Answer 19

Wernicke-Korsakoff

Question 20

SSRI risk on fetus

Answer 20

pulmonary hypertension and withdrawal

Question 21

men or women more likely to develop alcohol dependence?

Answer 21

men

Question 22

MDMA metabolized by to form HHMA

Answer 22

CYP2D6

Question 23

amphetamines excerpted via

Answer 23

urine - renal pathway

Question 24

benadryl can be false positive for

Answer 24

opiates

Question 25

mutated CHRN5 gene leads to ______ risk of tobacco dependence and ______ risk of cocaine dependence

Answer 25

increased - tobacco

decreased - cocaine

Question 26

can end stage liver dz cause pinpoint pupils?

Answer 26

yes

Question 27

70% of people with AUD will recover on their own without help after single drinking period lasting _____

Answer 27

3-4 years

Question 28

cocaine half life

Answer 28

1 hour