4 Flashcards
dynorphins bind to which opioid receptor and causes what
kappa –> dysphpria, decreased dopamine
12 mo prevalence of nicotine use disorder in US
20%
time to peak plasma concentration and time to peak effect for IV meth use vs smoking meth vs intranasal vs oral
IV: 15 min for both
smoking: 2.5 hrs for conc, 18 min for peak effect
intranasal: 3 hrs, 15 min for effect
oral: 3.5 hr (for both)
sertraline is false positive for
benzos
what features of urine would you look at to see if its been adulterated
- nitrites
- pH
what features of urine would you look at to see if its been diluted
- creatinine
- specific gravity
if someone on methadone needs acute pain management what do you do?
give them another opioid for acute pain management
dose of IM naltrexone
380 mg q4 weeks
how long is duration of cocaine?
30-60 minutes
12 month prevalence of AUD
13%
how does topiramate work to help reduce alcohol use?
antagonizes glutamate –> suppressed dopamine release in NA –> reduces reward
miscarriage is a possible withdrawal complication from…
opioids
after how many hours after drinking can you give disulfiram?
12 hours
how long should you wait to drink after getting disulfiram?
2 weeks
binge drinking defined as
drinking so much w/in 2 hours that BAC reaches 0.08g/DL (typically, 4 drinks for women, 5 for men)
