11 Flashcards

1
Q

D3 antagonists help substance use disorders how?

A

DAT blocker - methylphenidate analogue with slower onset of action

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

most common course for AUD In adults lasts how many years

A

3-4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

MDMA full name

A

3,4-Methyl​enedioxy​methamphetamin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

EEG for chronic cocaine user

A

decreased delta and theta - drowsy

increased alpha and beta - alert

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

benefits of pregabalin to gabapentin

A
  • quicker dose titration
  • faster pain relief
  • dosed BID not TID
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what percent of people with schizophrenia abuse drugs?

A

60% (37% with SUD)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how many days of sobriety after opioid before getting naltrexone?

A

7-10 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

do you need dose adjustments for naltrexone in patients with hepatic dysfunction?

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

difference between prevalence and incidence

A

incidence: #new cases/population

prevalence: #people with dz/population at particular time pt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Motivational Enhancement Therapy (MET) gist

A

gives patients feedback on their substance use compared to a normative group

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

which class of meds to avoid in patients who have used cocaine and have ACS?

A

beta blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

MDMA metabolized by

A

CYP2D6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

half life of MDMA

A

8 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

nitrite inhalants (aka poppers) MOA

A

peripheral vasodilation –> reduced cerebral perfusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Dexmedetomidine (precedex) moa

A

alpha 2 rec agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

which personality disorder most common with SUDs?

A

antisocial personality disorder

16
Q

buprenorphine MOA at each opioid rec

A

partial agonist at mu

antagonist at kappa

17
Q

which opioid receptor has highest abuse potential

A

mu

18
Q

1mg of lorazepam is how much alprazolam and diazepam

A

0.5 mg alprazolam

5mg diazepam

19
Q

proton pump inhibitors can cause false positive for what drug

A

marijuana

20
Q

which arrhythmia is most common in heavy alcohol use?

A

atrial fibrillation

21
Q

gene involved with efficacy of long-term methadone treatment

A

OPRD1

22
Q

12 month prevalence of nonmedical prescription opioid use disorder

A

0.9%