Sketchy Micro: Togavirus Group Flashcards
The Togaviruses are what kinds of viruses?
- Positive-sense ssRNA (orange tones)
* Enveloped (robes)
Which of the Togaviruses is an arbovirus? What are those viruses?
•The Eastern, Western, and Venezuelan equine encephalitis viruses (like the horse with the compass on its butt and the rider knocking his red turban off on the arch)
Rubella can cause ____________ lymphadenopathy.
cervical and occipital (like the king wearing the RUBies and rubbing his aching neck)
How does the Rubella rash present?
It is a maculopapular rash that starts on the head/face and moves downward.
(Think of the rubies falling off the king’s crown and landing on his body.)
The Rubella rash progresses more ________ than the Measles rash.
quickly
Rubella is transmitted by ____________ droplets.
respiratory (like the dewdrops falling off the palm fronds)
What is the “classic triad” of congenital Rubella?
- Sensorineural deafness (babies covering ears)
- Cataracts (babies with blank eyes)
- Patent ductus arteriosus (open aqueDUCT)
What are the “less classic” congenital Rubella symptoms?
- Purpuric blueberry muffin rash (blue gems on babies skin)
- Jaundice (the babies with the blue gems are yellow)
What are the adult symptoms of Rubella?
- Arthralgia (servants kneeling so long their knees hurt)
- Cervical/post-auricular lymphadeopathy (king rubbing his neck)
- Fever (king sweating)
The MMR vaccine is a ___________ vaccine.
live, attenuated
Think of the LIVE puppet show.
Those with CD4 counts above ______________ can receive the vaccine.
200 (like the “200 tickets” sign)
Like the Picorniviruses, Togaviruses make _______________.
a polyprotein precursor that gets cleaved in the cytosol
Think of the long string of tickets that gets broken into segments.
