5.10 Sex Determination Flashcards

0
Q

Gonadal sex is controlled by the presence or absence of

A

TDF testis determining factor (which is contained in the SRY region of Y chromosome)

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1
Q

Genetic Sex is determined with the presence or absence of which chromosome

A

Y

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2
Q

Precursor of female internal sec organs

A

Mullerian system

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3
Q

Precursor of male internal sex organs

A

Wolffian system

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4
Q

External genitalia is determined by presence or absence of

A

Testosterone
(-) testosterone - female genitalia develops
(+) testosterone - male genitalia develops

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5
Q

Urogenital folds differentiates to become
A. Labia majora
B. Labia minora

A

A. Labia majora - from labioscrotal swellings

B. Labia minora - correct answer

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6
Q

Gender of baby can be determined starting on the ____mos of pregnancy using the ultrasound

A

3rd month

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7
Q

Secondary sex characteristics are determined at
A. School age
B. Adulthood
C. Puberty

A

C. Puberty

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8
Q

Thelarche or breast enlargement start at what age in females

A

8 years old

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9
Q

Pubarche and menarche start at this age

A

11 years old

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10
Q

Thorarche and ovularche start at this age

A

14 years old

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11
Q

Diamond pubic hair

A. Male b. Female

A

Male- correct

Female- triangular

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12
Q

Characterized by Turner syndrome, absence of ovaries but with female external genitalia

A

Gonadal dysgenesis - only 1 X chromosome

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13
Q

Has XXX chromosome

A

Superfemale

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14
Q

An example of seminiferous tubule dysgenesis

A

Klinefelter’s syndrome - XY with additional X chromosome

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15
Q

Genetically female but gonads are male

A

Female pseudohermaphroiditism

16
Q

Congenital 17@-hydroxylase deficiency

A

Male pseudohermaphroiditism

17
Q

Occurs when a patient has 46 XY chromosome but with a normal female appearance

A

Androgen insensitivity syndrome

18
Q

Differentiate true precocious puberty and precocious puberty

A

True precocious - cerebral tumors

Precocious - adrenal tumors, Leydig and granulosa cell tumors

19
Q

External genitalia: DHT, internal genitalia : _____

A

AMH

20
Q
Determined at fertilization
A. Genetic sex
B. Genital sex
C. Gonadal sex
D. Physiological sex
A

A. Genetic sex

21
Q
Phenotypic sex
A. Genetic sex
B. Genital sex
C. Gonadal sex
D. Physiological sex
A

B. Genital sex

22
Q
Presence of SRY 
A. Genetic sex
B. Genital sex
C. Gonadal sex
D. Physiological sex
A

C. Gonadal sex - correct